The serial interval of COVID-19 from publicly reported confirmed cases
Zhanwei Du, Xiaoke Xu, Ye Wu, Lin Wang, Benjamin J Cowling, View ORCID ProfileLauren Ancel Meyers
doi: https://doi.org/10.1101/2020.02.19.20025452
Abstract
As a novel coronavirus (COVID-19) continues to emerge throughout China and threaten the globe, its transmission characteristics remain uncertain. Here, we analyze the serial intervals-the time period between the onset of symptoms in an index (infector) case and the onset of symptoms in a secondary (infectee) case-of 468 infector-infectee pairs with confirmed COVID-19 cases reported by health departments in 18 Chinese provinces between January 21, 2020, and February 8, 2020. The reported serial intervals range from -11 days to 20 days, with a mean of 3.96 days (95% confidence interval: 3.53-4.39), a standard deviation of 4.75 days (95% confidence interval: 4.46-5.07), and 12.1% of reports indicating pre-symptomatic transmission.
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