《Morgan Sheng加入Broad Institute和麻省理工学院》

  • 来源专题:人类遗传资源和特殊生物资源流失
  • 编译者: yanyf@mail.las.ac.cn
  • 发布时间:2019-05-05
  • Morgan Sheng是一位在基础研究和药物发现方面具有丰富经验的神经生物学家和医师科学家,他已加入麻省理工学院和哈佛大学,担任其最新核心成员,并担任该研究所斯坦利精神病研究中心的联合主任。经过十年的工业,他还将回到麻省理工学院,担任脑与认知科学系的神经科学教授,他将成为麦戈文脑研究所和Picower学习与记忆研究所的附属机构。

    作为斯坦利中心的联合主任,盛将与斯坦利中心主任史蒂文海曼合作,与Broad的治疗发展中心一起,监督该中心的科学愿景和方向,以及监督该中心的治疗工作。

    1994年,他在马萨诸塞州综合医院和哈佛医学院开始了他的学术生涯,以分子和细胞神经科学为中心,后来转到麻省理工学院担任Menicon神经科学教授。 2001年至2008年,他在麻省理工学院担任脑与认知科学系和生物系教授,是Picower学习与记忆研究所的成员,并且是霍华德休斯医学研究所的研究员。

    “摩根的开创性研究加速了对健康和疾病中大脑突触的理解,”Eric Lander说。 “我们很高兴让他加入Broad,他作为医生科学家和药物发现者的专业知识将帮助我们在精神疾病的理解和治疗方面取得进展。”

    Sheng在过去的10年里一直在Genentech,一家卓越的生物技术公司担任神经科学副总裁。在那里,他建立并领导了世界一流的神经科学部门和研究计划,重点是阐明病理机制,开发治疗神经退行性疾病和疼痛的新疗法,以及具有基本科学意义和治疗相关性的照明途径。 Sheng及其同事对突触减弱和缺失的分子机制,神经胶质细胞和先天免疫在神经退行性疾病中的作用以及遗传危险因素在阿尔茨海默病,帕金森病和额颞叶痴呆的发病机制中的作用做出了重要发现。

    在MGH和MIT期间,Sheng对突触的结构和功能(脑细胞之间的通信连接)的分子研究增强了我们对认知功能和功能障碍的神经基础的理解,包括学习和记忆,神经发育障碍和痴呆。他的研究揭示了突触后膜中蛋白质复合物的形态和复杂性,调节了神经元连接的显着可塑性。

    “我很高兴能回到学术界并在布罗德建立一个研究实验室,”盛说。 “我们处于一个关键时刻,正在出现的遗传和生物学见解可以改变我们研究,诊断和治疗精神疾病的方式。我期待加入这个创新研究人员社区,运用我的专业知识发现新疗法,改善精神疾病患者的生活。“

    “摩根作为医生和科学家的独特视角,以及他对转化神经科学的强大承诺,将促使斯坦利中心将生物学见解转化为精神疾病的新疗法,”海曼说。

    盛在英国伦敦完成了他的医学培训和普通医学住院医师。 1990年,他获得博士学位。哈佛大学分子遗传学专业,并在加州大学旧金山分校完成博士后研究。

    盛是英国皇家学会(英国),医学科学院(英国)和美国科学促进会的当选院士。盛的研究成果已被多个奖项所认可,包括基金会IPSEN神经可塑性奖和神经科学学会青年研究员奖。

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  • 《小王加入布罗德研究所和麻省理工学院》

    • 来源专题:人类遗传资源和特殊生物资源流失
    • 编译者:yanyf@mail.las.ac.cn
    • 发布时间:2019-06-19
    • 麻省理工学院和哈佛大学广泛研究所任命化学家兼分子工程师小王为核心研究所成员。王还将担任麻省理工学院化学系的助理教授。 “肖是一位非常富有创造力的科学家,他以远见卓识的方式研究神经系统,”布鲁德总裁兼创始人Eric Lander说。 “我们很高兴欢迎她来到这个社区。她努力将大脑绘制成许多尺度 - 从纳米到厘米到整个组织 - 将有助于照亮大脑的内部运作。“ Wang目前是Karl Deisseroth实验室斯坦福大学生命科学研究基金会的博士后研究员。在那里,她开发了分析完整组织中RNA的综合方法,将测序与成像相结合,以揭示大脑中各种细胞类型的位置,并找出这些细胞是如何连接的。 在Broad和麻省理工学院的实验室中,Wang将开发和应用新的化学,生物物理和基因组工具,以更好地了解分子水平的大脑功能和功能障碍。她将于2019年9月1日开始。 “为了真正理解像哺乳动物大脑这样复杂的器官,我们需要开发新的方法来绘制不同分辨率的神经连接,”Aviv Regev说,核心研究所成员,教员主席,克拉曼细胞天文台主任。 “我们很高兴肖将在Broad和麻省理工学院接受这一挑战。她将成为我们研究人员社区的宝贵而独特的成员,致力于构建和应用尖端工具,以帮助改善生物学理解和人类健康。“ 王女士收到她的B.S. 2010年在北京大学化学与分子工程专业,她与Jian Pei教授一起学习,并帮助开发荧光有机材料。她获得了博士学位。在2015年芝加哥大学的化学专业,她与川教授一起阐述了RNA修饰的细胞功能。在研究生期间,王先生被授予中国政府优秀自费留学生奖和伊丽莎白·R·诺顿化学研究卓越奖。她是霍华德休斯医学研究所博士后研究员和生命科学研究基金会博士后研究员。
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    • 来源专题:可再生能源
    • 编译者:武春亮
    • 发布时间:2024-02-17
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You may not alter the images provided, other than to crop them to size. A credit line must be used when reproducing images; if one is not provided below, credit the images to "MIT." Close Caption : The Climate Project at MIT, a major campus-wide effort, includes new arrangements for promoting cross-Institute collaborations and new mechanisms for engaging with outside partners to speed the development and implementation of climate solutions. Credits : Photo: Emily Dahl Previous image Next image MIT is preparing a major campus-wide effort to develop technological, behavioral, and policy solutions to some of the toughest problems now impeding an effective global climate response. The Climate Project at MIT, as the new enterprise is known, includes new arrangements for promoting cross-Institute collaborations and new mechanisms for engaging with outside partners to speed the development and implementation of climate solutions. MIT News spoke with Richard K. Lester, MIT’s vice provost for international activities, who has helped oversee the development of the project. Q: What is the Climate Project at MIT? A: In her inaugural address last May, President Kornbluth called on the MIT community to join her in a “bold, tenacious response” to climate change. The Climate Project at MIT is a response to that call. It aims to mobilize every part of MIT to develop, deliver, and scale up practical climate solutions, as quickly as possible. Play video At MIT, well over 300 of our faculty are already working with their students and research staff members on different aspects of the climate problem. Almost all of our academic departments and more than a score of our interdepartmental labs and centers are involved in some way. What they are doing is remarkable, and this decentralized structure reflects the best traditions of MIT as a “bottom up,” entrepreneurial institution. But, as President Kornbluth said, we must do much more. 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