Rhesus macaques can be effectively infected with SARS-CoV-2 via ocular conjunctival route
Wei Deng, Linlin Bao, Hong Gao, Zhiguang Xiang, Yajin Qu, Zhiqi Song, Shuran Gong, Jiayi Liu, Jiangning Liu, Pin Yu, Feifei Qi, Yanfeng Xu, Fengli Li, Chong Xiao, Qi Lv, Jing Xue, Qiang Wei, Mingya Liu, Guanpeng Wang, Shunyi Wang, Haisheng Yu, Xing Liu, Wenjie Zhao, Yunlin Han, Chuan Qin
doi: https://doi.org/10.1101/2020.03.13.990036
Abstract
The outbreak of Corona Virus Disease 2019 (COVID-19) is highly infectious and transmitted mainly through human-to-human transmission via respiratory droplets and direct or close contact to the patients with SARS-CoV-2. The other potential transmission routes remain to be further researched. In some clinical cases, samples of tears and conjunctival secretions from both SARS-CoV and SARS-CoV-2 patients with conjunctivitis displayed detectable viral RNA. A previous study reported the case of a clinician who was infected with SARS-CoV-2 while working with patients under all safeguards except eye protection.
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