《INFECTION,2月18日,2019 Novel coronavirus: where we are and what we know》

  • 来源专题:COVID-19科研动态监测
  • 编译者: zhangmin
  • 发布时间:2020-02-22
  • 2019 Novel coronavirus: where we are and what we know

    Zhangkai J. Cheng & Jing Shan

    Infection (2020)

    Abstract

    There is a current worldwide outbreak of a new type of coronavirus (2019-nCoV), which originated from Wuhan in China and has now spread to 17 other countries. Governments are under increased pressure to stop the outbreak spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak sites and from laboratories supporting the investigation. This paper aggregates and consolidates the virology, epidemiology, clinical management strategies from both English and Chinese literature, official news channels, and other official government documents. In addition, by fitting the number of infections with a single-term exponential model, we report that the infection is spreading at an exponential rate, with a doubling period of 1.8 days.

  • 原文来源:https://link.springer.com/article/10.1007%2Fs15010-020-01401-y
相关报告
  • 《IJID,3月12日,The SARS-CoV-2 outbreak: what we know》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-13
    • The SARS-CoV-2 outbreak: what we know DiWu, TiantianWu, QunLiu, ZhicongYang Show more https://doi.org/10.1016/j.ijid.2020.03.004 Abstract There is a current worldwide outbreak of the novel coronavirus Covid-19 (coronavirus disease 2019; the pathogen called SARS-CoV-2; previously 2019-nCoV), which originated from Wuhan in China and has now spread to 6 continents including 66 countries, as of 24:00 on March 2, 2020. Governments are under increased pressure to stop the outbreak spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak site and from laboratories supporting the investigation. This paper aggregates and consolidates the epidemiology, clinical manifestations, diagnosis, treatments and preventions of this new type of coronavirus.
  • 《MedRxiv,2月18日,Early evaluation of transmission control measures in response to the 2019 novel coronavirus outbreak in China》

    • 来源专题:COVID-19科研动态监测
    • 编译者:xuwenwhlib
    • 发布时间:2020-02-19
    • Early evaluation of transmission control measures in response to the 2019 novel coronavirus outbreak in China Huaiyu Tian, Yonghong Liu, Yidan Li, Moritz U. G. Kraemer, Bin Chen, Chieh-Hsi Wu, Jun Cai, Bingying Li, Bo Xu, Qiqi Yang, Ben Wang, Peng Yang, Yujun Cui, Yimeng Song, Pai Zheng, Quanyi Wang, Ottar N Bjornstad, Ruifu Yang, Bryan Grenfell, Oliver Pybus, Christopher Dye doi: https://doi.org/10.1101/2020.01.30.20019844 Abstract Background: An ongoing outbreak of a novel coronavirus disease (COVID-19) was first reported in December 2019 in Wuhan city, Hubei Province, and has spread throughout China and to other countries. On 23 January 2020, in an attempt to contain the epidemic, non-essential travel was prohibited in and out of Wuhan city, a major transport hub and conurbation of 11 million people. Since then China has implemented nationwide its highest level (Level 1) of emergency response to further contain the spread of infection within and among cities. Methods: We used generalized linear regression models to investigate the effect of the type and timing of transmission control measures on the spread of COVID-19 from Wuhan city, and on the growth of the epidemic in 296 other cities across China. In addition to the Wuhan city shutdown, as part of the emergency response, entertainment venues were closed, public gatherings banned, intra-city public transport (bus and subway rail) suspended, and travel to and from other cities prohibited. Findings: The Wuhan city travel ban slowed the dispersal of infection to other cities by an estimated 2.91 days (95% CI: 2.54-3.29) on average. Among the other urban centres across mainland China, cities that implemented control measures pre-emptively, before the first case was reported, had 37% fewer cases in the week following the first reported case (13.0, 95%CI 7.1-18.8) compared with cities starting control after the first case (20.6, 95%CI: 14.5-26.8). Among individual control measures investigated, the most effective were suspending intra-city public transport, and closing entertainment venues and banning public gatherings. Interpretation: The implementation of transmission control measures slowed the dispersal of infection from its origin in Wuhan city and reduced the numbers of cases reported during the early stages of the epidemic in hundreds of other Chinese cities. *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.