《LANCET,4月7日,Making decisions to mitigate COVID-19 with limited knowledge》

  • 来源专题:COVID-19科研动态监测
  • 编译者: xuwenwhlib
  • 发布时间:2020-04-08
  • Making decisions to mitigate COVID-19 with limited knowledge

    Weituo Zhang

    Bi-yun Qian

    Published:April 07, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30280-2

    On March 11, 2020, WHO declared the coronavirus disease 2019 (COVID-19) outbreak a global pandemic. Aggressive actions should be taken immediately to mitigate the spread of severe acute respiratory syndrome coronavirus 2. In their Comment, Yonghong Xiao and Mili Estee Torok1 rightly stated that infection prevention and control measures should be based on sound scientific principles. However, we disagree with the authors' views on certain measures that they consider to have “no scientific basis and have proven to be ineffective”. A difference exists between measures with unknown effectiveness and those that have been proven ineffective or of no value.

    We disagree with Xiao and Torok's view that “the practice of blocking traffic and lockdown of villages is of no value for the prevention and control of COVID-19”. One of the references provided to support this statement was a local transport authority policy reported in a newspaper, which should not be considered as scientific evidence. Several studies have been done to assess the effectiveness of travel restrictions,2, 3 and the benefit of such restrictions might vary in different settings. Further studies and more data are required to reach a solid conclusion.

  • 原文来源:https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30280-2/fulltext
相关报告
  • 《LANCET,4月7日,COVID-19, school closures, and child poverty: a social crisis in the making》

    • 来源专题:COVID-19科研动态监测
    • 编译者:xuwenwhlib
    • 发布时间:2020-04-08
    • COVID-19, school closures, and child poverty: a social crisis in the making Wim Van Lancker Zachary Parolin Open AccessPublished:April 07, 2020DOI:https://doi.org/10.1016/S2468-2667(20)30084-0 While coronavirus disease 2019 (COVID-19) continues to spread across the globe, many countries have decided to close schools as part of a physical distancing policy to slow transmission and ease the burden on health systems. The UN Educational, Scientific and Cultural Organization estimates that 138 countries have closed schools nationwide, and several other countries have implemented regional or local closures. These school closures are affecting the education of 80% of children worldwide. Although scientific debate is ongoing with regard to the effectiveness of school closures on virus transmission,1 the fact that schools are closed for a long period of time could have detrimental social and health consequences for children living in poverty, and are likely to exacerbate existing inequalities. We discuss two mechanisms through which school closures will affect poor children in the USA and Europe.
  • 《4月7日_以有限的知识做出缓解COVID-19的决策》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-04-09
    • 1.时间:2020年4月7日 2.机构或团队:上海交通大学医学院 3.事件概要: 上海交通大学医学院的科研人员在The Lancet Infectious Diseases期刊在线发表题为“Making decisions to mitigate COVID-19 with limited knowledge”的通讯文章。文章提到,Xiao 等人[1]正确的指出,感染的预防和控制措施应基于可靠的科学原理。然而,本文作者不同意Xiao等人在某些措施上的观点,即其认为这些措施“没有科学依据并且被证明是无效的”。本文作者认为,有效性未知的措施与证明无效或无价值的措施之间存在区别。 本文作者不同意Xiao等人的某些观点,即“阻塞交通和封锁村庄的做法对预防和控制COVID-19毫无价值”, 因其提供支持该说法的参考资料之一是报纸上报道的一项当地交通主管部门的政策,这不应视为科学证据。文章指出已经进行了几项研究以评估出行限制的有效性,并且这种限制的好处在不同的情况下可能有所不同,需要进一步的研究和更多的数据才能得出可靠的结论。 文章指出,关于COVID-19患者的住院治疗,Xiao等人建议不要给患者服用疗效未知的药物。但是,考虑到目前尚无有效的治疗方法,本文作者认为标签外用药可或有同情性用药使用应视为是合乎伦理的,特别是对于有生命危险的感染患者。但是,在考虑使用这些药物时,应明确药物的安全性,并且临床医生应谨慎权衡使用风险和潜在收益。 在COVID-19大流行的紧急阶段,必须利用现有的稀少数据来做出公共卫生应对或临床管理方面的决策。正在进行的研究将逐步建立科学证据。但是,有充分理由但缺乏数据支持的措施(例如出行限制、封锁和同情用药),也应视为备选方案,并应不断进行评估和修订。 4.附件: 原文链接:https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30280-2/fulltext [1] Xiao Y, Torok ME. Taking the right measures to control COVID-19.Lancet Infect Dis. 2020. (published online March 5)