登录
 机构网站
  1. 首页
  2. 情报产品
  3. 快讯详情

《CKJ，6月6日，Characterization of acute kidney injury in critically ill patients with severe coronavirus disease 2019》

  • 来源专题：COVID-19科研动态监测
  • 编译者： xuwenwhlib
  • 发布时间：2020-06-07

  • Characterization of acute kidney injury in critically ill patients with severe coronavirus disease 2019

    Sébastien Rubin, Arthur Orieux, Renaud Prevel, Antoine Garric, Marie-Lise Bats, Sandrine Dabernat, Fabrice Camou, Olivier Guisset, Nahema Issa, Gaelle Mourissoux ... Show more

    Clinical Kidney Journal, sfaa099, https://doi.org/10.1093/ckj/sfaa099

    Published: 06 June 2020

    Abstract

    Background

    Coronavirus disease 2019 (COVID-19)-associated acute kidney injury (AKI) frequency, severity and characterization in critically ill patients has not been reported.

    Methods

    Single-centre cohort performed from 3 March 2020 to 14 April 2020 in four intensive care units in Bordeaux University Hospital, France. All patients with COVID-19 and pulmonary severity criteria were included. AKI was defined using Kidney Disease: Improving Global Outcomes (KDIGO) criteria. A systematic urinary analysis was performed. The incidence, severity, clinical presentation, biological characterization (transient versus persistent AKI; proteinuria, haematuria and glycosuria) and short-term outcomes were evaluated.

  • 原文来源：https://academic.oup.com/ckj/advance-article/doi/10.1093/ckj/sfaa099/5854260?searchresult=1
144浏览量
原文链接
相关报告

  • 《SSRN，2月6日，Clinical Course and Outcomes of Critically Ill Patients of 2019 Novel Coronavirus Pneumonia》
    • 来源专题：COVID-19科研动态监测
    • 编译者：xuwenwhlib
    • 发布时间：2020-02-07
    • Clinical Course and Outcomes of Critically Ill Patients of 2019 Novel Coronavirus Pneumonia 19 Pages Posted: 6 Feb 2020 Corresponding Author: You Shang, Ph.D., M.D. Wuhan Union Hospital Wuhan, Hubei CHINA First Author: Xiaobo Yang Abstract Background: An ongoing outbreak of pneumonia associated with the 2019 novel coronavirus (2019-nCoV) started in December 2019, in Wuhan, China. Information on critically ill patients of 2019-nCoV infection is extremely limited. We aimed to describe the clinical course and outcomes of critically ill patients of 2019-nCoV pneumonia. Methods: In this retrospective study, 52 critically ill patients out of 710 patients, who were diagnosed with 2019-nCoV pneumonia in Wuhan Jinyintan Hospital between the onset of the outbreak and January 26, 2020, were investigated. Only patients treated with high flow nasal cannula or mechanical ventilator were included. Patients who were deceased or who had been hospitalized for at least 14 days were considered for the case reviewed. Epidemiological, demographic, clinical and laboratory data were collected and analyzed to explore the differences between survivors and non-survivors. Findings: Of the 52 critically ill patients, the average age was 59.7 ±13.3 years(mean ± standard deviation), 35 (67.3%) were male, 21 (40.4%) had chronic illness, 51 (98.1%) had fever, 35 (67.3%) had ARDS and 37 (71.2%) required mechanical ventilation. The duration from onset of symptoms to radiological diagnosis of pneumonia was 5 [3-7] (median [interquartile range]) days. Thirty-three (57.7%) patients deceased, and the duration from hospital admission to death was 7 [3 - 11] days. Compared with survivors, non-survivors were older (64.7 ± 11.1 years vs 59.7 ± 13.3 years, p = 0.001), received higher fraction of oxygen therapy (0.87 ± 0.16 vs 0.70 ± 0.18, p = 0.004), developed more ARDS (83.3% vs 45.4%, p = 0.007), required more mechanical ventilation (93.3% vs 40.9%, p = 0.003) and were more likely to be on extracorporeal membrane oxygenation (16.7% vs 4.6%, p = 0.06).
    148浏览量
    原文链接

  • 《MedRxiv，3月8日，Acute Myocardial Injury of Patients with Coronavirus Disease 2019》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-03-09
    • Acute Myocardial Injury of Patients with Coronavirus Disease 2019 Huayan Xu, Keke Hou, Hong Xu, Zhenlin Li, Huizhu Chen, Na Zhang, Rong Xu, Hang Fu, Ran Sun, Lingyi Wen, Linjun Xie, Hui Liu, Kun Zhang, Joseph B Selvanayagam, Chuan Fu, Shihua Zhao, Zhigang Yang, Ming Yang, Yingkun Guo doi: https://doi.org/10.1101/2020.03.05.20031591 Abstract Background: Since the outbreak of the Coronavirus Disease 2019 (COVID-19) in China, respiratory manifestations of the disease have been observed. However, as a fatal comorbidity, acute myocardial injury (AMI) in COVID-19 patients has not been previously investigated in detail. We investigated the clinical characteristics of COVID-19 patients with AMI and determined the risk factors for AMI in them. Methods: We analyzed data from 53 consecutive laboratory-confirmed and hospitalized COVID-19 patients (28 men, 25 women; age, 19-81 years). We collected information on epidemiological and demographic characteristics, clinical features, routine laboratory tests (including cardiac injury biomarkers), echocardiography, electrocardiography, imaging findings, management methods, and clinical outcomes. *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.
    158浏览量
    原文链接