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《LANCET，3月17日，COVID-19 in pregnant women》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-03-18

  • COVID-19 in pregnant women

    Manuel B Schmid

    Jehudith Fontijn

    Nicole Ochsenbein-Kölble

    Christoph Berger

    Dirk Bassler

    Published:March 17, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30175-4

    With interest, we read the recommendation on the management of pregnant women with suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Guillaume Favre and colleagues.1 Some of the recommendations made in the flowsheet of their Correspondence have long-term consequences (eg, termination of pregnancy, no breastfeeding) of an unforeseeable extent, are harmful when applied to the general population (eg, early cord clamping in extremely preterm infants, no breastfeeding, separation of the mother from the newborn), are not proven to reduce the risk of transmission in other viral illnesses (eg, early cleaning of the newborn), and are contradictory to the current recommendations by the US Centers for Disease Control and Prevention (CDC) for the management of coronavirus disease 2019 (COVID-19; eg, testing of asymptomatic people, no breastfeeding).

  • 原文来源：https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30175-4/fulltext
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  • 《LANCET，3月17日，COVID-19 in pregnant women – Authors' reply》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-03-18
    • COVID-19 in pregnant women – Authors' reply David Baud Eric Giannoni Léo Pomar Xiaolong Qi Karin Nielsen-Saines Didier Musso et al. Show all authors Published:March 17, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30192-4 We are grateful for the concerns of Manuel Schmidt and colleagues about our previous guidelines1 for pregnant women with suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. At the time we developed the algorithm (February, 2020), there were no data regarding potential vertical transmission from infected mothers and outcomes in newborns. To date, there has been no evidence of vertical transmission of coronavirus disease 2019 (COVID-19) based on two small clinical series.2, 3 According to WHO, delayed umbilical cord clamping is highly unlikely to increase the risk of transmitting pathogens from the mother to the fetus even in the case of maternal infection.4 Because the vernix caseosa contains antimicrobial peptides, we recommend leaving it in place until 24 h after birth.5 New data examining neonates from infected mothers could be reassuring, but transmission after birth via contact with infectious respiratory secretions is still a concern, and physical separation of mother from child should be considered. Separation is a standard practice in pulmonary tuberculosis and is discussed in cases of maternal influenza infection.6 Therefore, separation of the mother and her newborn baby should be individually discussed by an interdisciplinary team, considering local facilities and risk factors for adverse neonatal outcomes, such as prematurity and fetal distress.
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  • 《LANCET，3月24日，Management of pregnant women infected with COVID-19》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-03-25
    • Management of pregnant women infected with COVID-19 Yongwen Luo Kai Yin Published:March 24, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30191-2 Since December, 2019, the outbreak of coronavirus disease 2019 (COVID-19), which originated in Wuhan, China, has become a global public health threat. On Feb 28, 2020, WHO upgraded their assessment of the risk of spread and the risk of impact of COVID-19 to very high at global level. By March 10, 2020, 116?166 cases have been reported globally, causing 4088 deaths. The epidemic has spread to 118 countries around the world.
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