《Nature,3月13日,Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding》

  • 来源专题:COVID-19科研动态监测
  • 编译者: zhangmin
  • 发布时间:2020-03-14
  • Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

    Yi Xu, Xufang Li, Bing Zhu, Huiying Liang, Chunxiao Fang, Yu Gong, Qiaozhi Guo, Xin Sun, Danyang Zhao, Jun Shen, Huayan Zhang, Hongsheng Liu, Huimin Xia, Jinling Tang, Kang Zhang & Sitang Gong

    Nature Medicine (2020)

    Abstract

    We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA. Symptoms in these cases were nonspecific and no children required respiratory support or intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the infection in adult cases. Notably, eight children persistently tested positive on rectal swabs even after nasopharyngeal testing was negative, raising the possibility of fecal–oral transmission.

  • 原文来源:https://www.nature.com/articles/s41591-020-0817-4
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    • 编译者:zhangmin
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    • 编译者:zhangmin
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