《MedRxiv,3月16日,A Method to Model Outbreaks of New Infectious Diseases with Pandemic Potential such as COVID-19》

  • 来源专题:COVID-19科研动态监测
  • 编译者: zhangmin
  • 发布时间:2020-03-17
  • A Method to Model Outbreaks of New Infectious Diseases with Pandemic Potential such as COVID-19

    Willem G Odendaal

    doi: https://doi.org/10.1101/2020.03.11.20034512

    Abstract

    The emergence of the novel coronavirus (a.k.a. COVID-19, SARS-CoV-2) out of Wuhan, Hubei Province, China caught the world by surprise. As the outbreak began to spread outside of China, too little was known about the virus to model its transmission with any acceptable accuracy. World governments responded to rampant minformation about the virus leading to collatoral disasters, such as plunging financial markets, that could have been avoided if better models of the outbreak had been available. This is an engineering approach to model the spread of a new infectious disease from sparse data when little is known about the infectious agent itself. The most sought after estimate is the projected number of people who may be contagious, but still be within the incubation period thus remaining asymptomatic and undetected.

    *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.

  • 原文来源:https://www.medrxiv.org/content/10.1101/2020.03.11.20034512v1
相关报告
  • 《MedRxiv,3月24日,A New, Simple Projection Model for COVID-19 Pandemic》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-25
    • A New, Simple Projection Model for COVID-19 Pandemic Jian Lu doi: https://doi.org/10.1101/2020.03.21.20039867 Abstract With the worldwide outbreak of COVID-19, an accurate model to predict how the coronavirus pandemic will evolve becomes important and urgent to help policy makers in different countries address the epidemic outbreak and determine policies to control spread more efficiently and effectively. Unlike the classic public health and virus propagation models, this new projection model takes government intervention and public response into account to make reliable projections of the outbreak 10 days to 2 weeks in advance. *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.
  • 《MedRxiv,3月16日,Duration of viral detection in throat and rectum of a patient with COVID-19》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-17
    • Duration of viral detection in throat and rectum of a patient with COVID-19 Le Van Tan, Nghiem My Ngoc, Bui Thi Ton That, Le Thi Tam Uyen, Nguyen Thi Thu Hong, Nguyen Thi Phuong Dung, Le Nguyen Truc Nhu, Tran Tan Thanh, Dinh Nguyen Huy Man, Nguyen Thanh Phong, Tran Tinh Hien, Nguyen Thanh Truong, Guy Thwaites, Nguyen Van Vinh Chau doi: https://doi.org/10.1101/2020.03.07.20032052 Abstract The rapid spread of coronavirus disease 2019 (COVID-19) raises concern about a global pandemic. Knowledge about the duration of viral shedding remains important for patient management and infection control. We report the duration of viral detection in throat and rectum of a COVID-19 patient treated at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam. Despite clinical recovery, SARS-CoV-2 RNA remained detectable by real time RT-PCR in throat and rectal swabs until day 11 and 18 of hospitalization, respectively. Because live SARS-CoV-2 has been successfully isolated from a stool sample from a COVID-19 patient in China, the results demonstrate that COVID-19 patients may remain infectious for long periods, and fecal-oral transmission may be possible. Therefore, our finding has important implications for infection control. *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.