Duration of viral detection in throat and rectum of a patient with COVID-19
Le Van Tan, Nghiem My Ngoc, Bui Thi Ton That, Le Thi Tam Uyen, Nguyen Thi Thu Hong, Nguyen Thi Phuong Dung, Le Nguyen Truc Nhu, Tran Tan Thanh, Dinh Nguyen Huy Man, Nguyen Thanh Phong, Tran Tinh Hien, Nguyen Thanh Truong, Guy Thwaites, Nguyen Van Vinh Chau
doi: https://doi.org/10.1101/2020.03.07.20032052
Abstract
The rapid spread of coronavirus disease 2019 (COVID-19) raises concern about a global pandemic. Knowledge about the duration of viral shedding remains important for patient management and infection control. We report the duration of viral detection in throat and rectum of a COVID-19 patient treated at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam. Despite clinical recovery, SARS-CoV-2 RNA remained detectable by real time RT-PCR in throat and rectal swabs until day 11 and 18 of hospitalization, respectively. Because live SARS-CoV-2 has been successfully isolated from a stool sample from a COVID-19 patient in China, the results demonstrate that COVID-19 patients may remain infectious for long periods, and fecal-oral transmission may be possible. Therefore, our finding has important implications for infection control.
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