High-dose intravenous immunoglobulin as a therapeutic option for deteriorating patients with Coronavirus Disease 2019
Wei Cao, M.D, Xiaosheng Liu, PhD, Tao Bai, M.D, Hongwei Fan, M.D, Ke Hong, M.D, Hui Song, M.D, Yang Han, PhD, Ling Lin, M.D, Lianguo Ruan, M.D, Taisheng Li, M.D, PhD Author Notes
Open Forum Infectious Diseases, ofaa102, https://doi.org/10.1093/ofid/ofaa102
Published: 21 March 2020
Abstract
The outbreak of Coronavirus Disease 2019 (COVID-19) has spread rapidly in China. Till now, no definite effective treatment has been identified. We reported on three patients of severe COVID-19 who received high-dose intravenous immunoglobulin (IVIg) with satisfactory recovery. Based on these observations, randomized studies of high-dose IVIg should be considered in deteriorating patients infected with COVID-19.