Effects of Hydroxychloroquine Treatment on QT Interval
Author links open overlay panelMatthewHooksMDaBradleyBartMDabOrlyVardenyPharmD, MSacAndersWestanmoPharmD, MBAdSelçukAdabagMD, MSab
Show more
https://doi.org/10.1016/j.hrthm.2020.06.029
Abstract
Background
Hydroxychloroquine (HCQ) has been promoted as a potential treatment for COVID-19 but there are safety concerns.
Objectives
To determine the effect of HCQ treatment on QT interval
Methods
We retrospectively studied the electrocardiograms of 819 patients treated with HCQ for rheumatologic diseases from 2000 to 2020. The primary outcome was corrected QT (QTc) interval, by Bazett formula, during HCQ therapy.