Potential impact of seasonal forcing on a SARS-CoV-2 pandemic
Richard A Neher, Robert Dyrdak, Valentin Druelle, Emma B Hodcroft, Jan Albert
doi: https://doi.org/10.1101/2020.02.13.20022806
Abstract
A novel coronavirus (SARS-CoV-2) first detected in Wuhan, China, has spread rapidly since December 2019, causing more than 80,000 confirmed infections and 2,700 fatalities (as of Feb 27, 2020). Imported cases and transmission clusters of various sizes have been reported globally suggesting a pandemic is likely. Here, we explore how seasonal variation in transmissibility could modulate a SARS-CoV-2 pandemic. Data from routine diagnostics show a strong and consistent seasonal variation of the four endemic coronaviruses (229E, HKU1, NL63, OC43) and we parameterize our model for SARS-CoV-2 using these data.
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