Early dynamics of transmission and control of COVID-19: a mathematical modelling study
Adam J Kucharski, PhD
Timothy W Russell, PhD
Charlie Diamond, MSc
Yang Liu, PhD
John Edmunds, PhD
Sebastian Funk, PhD
et al.
Open AccessPublished:March 11, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30144-4
Summary
Background
An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to 95?333 confirmed cases as of March 5, 2020. Understanding the early transmission dynamics of the infection and evaluating the effectiveness of control measures is crucial for assessing the potential for sustained transmission to occur in new areas. Combining a mathematical model of severe SARS-CoV-2 transmission with four datasets from within and outside Wuhan, we estimated how transmission in Wuhan varied between December, 2019, and February, 2020. We used these estimates to assess the potential for sustained human-to-human transmission to occur in locations outside Wuhan if cases were introduced.