Rapid metagenomic characterization of a case of imported COVID-19 in Cambodia
Jessica E Manning, Jennifer A Bohl, Sreyngim Lay, Sophana Chea, Sovann Ly, Yi Sengdoeurn, Seng Heng, Chan Vuthy, Katarina Kalantar, Vida Ahyong, Michelle Tan, Jonathan Sheu, Christina M Tato, Joseph DeRisi, Laurence Baril, Philippe Dussart, Veasna Duong, Erik A Karlsson
doi: https://doi.org/10.1101/2020.03.02.968818
Abstract
Rapid production and publication of pathogen genome sequences during emerging disease outbreaks provide crucial public health information. In resource-limited settings, especially near an outbreak epicenter, conventional deep sequencing or bioinformatics are often challenging. Here we successfully used metagenomic next generation sequencing on an iSeq100 Illumina platform paired with an open-source bioinformatics pipeline to quickly characterize Cambodia's first case of COVID-2019.
*注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.