Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Luca Ferretti1,*, Chris Wymant1,*, Michelle Kendall1, Lele Zhao1, Anel Nurtay1, Lucie Abeler-Dörner1, Michael Parker2, David Bonsall1,3,†, Christophe Fraser1,4,†,‡
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Science 08 May 2020:
Vol. 368, Issue 6491, eabb6936
DOI: 10.1126/science.abb6936
Structured Abstract
INTRODUCTION
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), has clear potential for a long-lasting global pandemic, high fatality rates, and incapacitated health systems. Until vaccines are widely available, the only available infection prevention approaches are case isolation, contact tracing and quarantine, physical distancing, decontamination, and hygiene measures. To implement the right measures at the right time, it is of crucial importance to understand the routes and timings of transmission.
RATIONALE
We used key parameters of epidemic spread to estimate the contribution of different transmission routes with a renewal equation formulation, and analytically determined the speed and scale for effective identification and contact tracing required to stop the epidemic.