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《CELL，4月8日，Epidemiological and clinical characteristics of COVID-19 in adolescents and young adults》

  • 来源专题：COVID-19科研动态监测
  • 编译者： xuwenwhlib
  • 发布时间：2020-04-09

  • Epidemiological and clinical characteristics of COVID-19 in

    adolescents and young adults

    Jiaqiang Liao, Ph.D.1#*

    , Shibing Fan, MD.2#, Jing Chen, BD.3#

    , Jianglin Wu, BD.4#

    Public summary

    ? Adolescents and young adults are more involved in frequent socialactivity, overseas studying, and international working and traveling,

    which might make them susceptible to worldwide spread of the coronavirus

    disease 2019 (COVID-19).

    ? Adolescent and younger patients of COVID-19 had a median incubation period

    of 8 days and 50% of their family contacts could develop illness within

    1.4 days after exposure.

    ? Three asymptomatic patients of COVID-19 have infected their family

    contacts.

    ? Although most of the adolescent and young adult patients of COVID-19 have

    better prognosis outcomes after treatment, few of them showed severe

    clinical signs and symptoms such as bacterial pneumonia changes by Chest

    CT findings, fever, and shortness of breath.

  • 原文来源：https://marlin-prod.literatumonline.com/pb-assets/journals/society/the-innovation/PDFs/EpidemClinicalCharacteristics.pdf
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  • 《MedRxiv，3月12日，Epidemiological and clinical characteristics of COVID-19 in adolescents and young adults》
    • 来源专题：COVID-19科研动态监测
    • 编译者：xuwenwhlib
    • 发布时间：2020-03-13
    • Epidemiological and clinical characteristics of COVID-19 in adolescents and young adults View ORCID ProfileJiaqiang Liao, Shibing Fan Sr., Jing Chen, Jianglin Wu, Shunqing Xu, Yuming Guo, Chunhui Li, Xianxiang Zhang, Chuansha Wu, Huaming Mou, Chenxi Song, Feng Li, Guicheng Wu, Jingjing Zhang, Lian Guo, Huawen Liu, Jinglong Lv, Lixin Xu, Chunhui Lang doi: https://doi.org/10.1101/2020.03.10.20032136 Abstract Background: Adolescents and young adults might play a key role in the worldwide spread of Coronavirus Disease 2019 (COVID-19), because they are more involved in overseas studying, business, working, and travelling. However, the epidemiological and clinical characteristics of them are still unknown. Methods: We collected data of 46 confirmed COVID-19 patients aged 10 to 35 years from the study hospital. The demographics, epidemiological, and clinical data were collected. Several key epidemiological parameters, the asymptomatic cases and transmission to their family members and the clinical characteristics at admission, and during treatment were summarized. RESULTS: Of 46 confirmed patients, 14 patients (47.3%) were aged from 10 to 24 years, and 24 (52.7%) patients were male. The mean incubation period for symptomatic cases was 6.6 days (95% confidence interval (CI) 4.4 - 9.6). The median serial interval was 1.9 days (95% CI 0.4 - 6.2). Three of asymptomatic cases showed the transmission to their family members. Only 1 patient was identified as severe cases at admission. The common symptoms at admission were dry cough (34, 91.0%), and fever (29, 69.0%). Nearly 60% of the patients had showed ground-glass opacity by chest CT findings. Three patients developed acute kidney injury during treatment. Majority of patients (78.3%) were discharged by the end of the follow-up. Conclusions: The adolescent and young adult patients of COVID-19 had a long incubation period, and a short serial interval. The transmission to their family contactors occurred in asymptomatic cases. Few of the study patients have developed complications during treatment. *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.
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    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-04-24
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