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《Nature，4月23日，Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-04-24

  • Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

    The COVID-19 Investigation Team

    Nature Medicine (2020)

    Abstract

    Data on the detailed clinical progression of COVID-19 in conjunction with epidemiological and virological characteristics are limited. In this case series, we describe the first 12 US patients confirmed to have COVID-19 from 20 January to 5 February 2020, including 4 patients described previously1,2,3. Respiratory, stool, serum and urine specimens were submitted for SARS-CoV-2 real-time reverse-transcription polymerase chain reaction (rRT-PCR) testing, viral culture and whole genome sequencing. Median age was 53 years (range: 21–68); 8 patients were male. Common symptoms at illness onset were cough (n = 8) and fever (n = 7). Patients had mild to moderately severe illness; seven were hospitalized and demonstrated clinical or laboratory signs of worsening during the second week of illness.

  • 原文来源：https://www.nature.com/articles/s41591-020-0877-5
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  • 《MedRxiv，3月12日，First 12 patients with coronavirus disease 2019 (COVID-19) in the United States》
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    • 编译者：xuwenwhlib
    • 发布时间：2020-03-13
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