COVIDep: A web-based platform for real-time reporting of vaccine target recommendations for SARS-CoV-2
View ORCID ProfileSyed Faraz Ahmed, View ORCID ProfileAhmed A. Quadeer, View ORCID ProfileMatthew R. McKay
doi: https://doi.org/10.1101/2020.05.23.111385
Abstract
We introduce COVIDep (https://COVIDep.ust.hk), a web-based platform that provides immune target recommendations for guiding SARS-CoV-2 vaccine development. COVIDep implements a protocol that pools together publicly-available genetic data for SARS-CoV-2 and epitope data for SARS-CoV to identify B cell and T cell epitopes that present potential immune targets for SARS-CoV-2. Correspondences between outputs of COVIDep and emerging experimental results are also indicated. The platform is user-friendly, flexible, and based on up-to-date data. It may help guide vaccine designs and associated experimental studies for SARS-CoV-2.