登录
 机构网站
  1. 首页
  2. 情报产品
  3. 快讯详情

《PNAS，6月11日，Identifying airborne transmission as the dominant route for the spread of COVID-19》

  • 来源专题：COVID-19科研动态监测
  • 编译者： xuwenwhlib
  • 发布时间：2020-06-14

  • Identifying airborne transmission as the dominant route for the spread of COVID-19
    Renyi Zhang,  View ORCID ProfileYixin Li, Annie L. Zhang,  View ORCID ProfileYuan Wang, and Mario J. Molina
    PNAS first published June 11, 2020 https://doi.org/10.1073/pnas.2009637117
    Contributed by Mario J. Molina, May 16, 2020 (sent for review May 14, 2020; reviewed by Manish Shrivastava and Tong Zhu)

    Abstract
    Various mitigation measures have been implemented to fight the coronavirus disease 2019 (COVID-19) pandemic, including widely adopted social distancing and mandated face covering. However, assessing the effectiveness of those intervention practices hinges on the understanding of virus transmission, which remains uncertain. Here we show that airborne transmission is highly virulent and represents the dominant route to spread the disease. By analyzing the trend and mitigation measures in Wuhan, China, Italy, and New York City, from January 23 to May 9, 2020, we illustrate that the impacts of mitigation measures are discernable from the trends of the pandemic. Our analysis reveals that the difference with and without mandated face covering represents the determinant in shaping the pandemic trends in the three epicenters. This protective measure alone significantly reduced the number of infections, that is, by over 78,000 in Italy from April 6 to May 9 and over 66,000 in New York City from April 17 to May 9. Other mitigation measures, such as social distancing implemented in the United States, are insufficient by themselves in protecting the public. We conclude that wearing of face masks in public corresponds to the most effective means to prevent interhuman transmission, and this inexpensive practice, in conjunction with simultaneous social distancing, quarantine, and contact tracing, represents the most likely fighting opportunity to stop the COVID-19 pandemic. Our work also highlights the fact that sound science is essential in decision-making for the current and future public health pandemics.

  • 原文来源：https://www.pnas.org/content/early/2020/06/10/2009637117
36浏览量
原文链接
相关报告

  • 《MedRixv，2月25日，Characterizing the transmission and identifying the control strategy for COVID-19 through epidemiological modeling》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-02-26
    • Characterizing the transmission and identifying the control strategy for COVID-19 through epidemiological modeling Ke K. Zhang, Linglin Xie, Lauren Lawless, Huijuan Zhou, Guannan Gao, Chengbin Xue doi: https://doi.org/10.1101/2020.02.24.20026773 Abstract The outbreak of the novel coronavirus disease, COVID-19, originating from Wuhan, China in early December, has infected more than 70,000 people in China and other countries and has caused more than 2,000 deaths. As the disease continues to spread, the biomedical society urgently began identifying effective approaches to prevent further outbreaks. Through rigorous epidemiological analysis, we characterized the fast transmission of COVID-19 with a basic reproductive number 5.6 and proved a sole zoonotic source to originate in Wuhan. No changes in transmission have been noted across generations. By evaluating different control strategies through predictive modeling and Monte carlo simulations, a comprehensive quarantine in hospitals and quarantine stations has been found to be the most effective approach. Government action to immediately enforce this quarantine is highly recommended. *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.
    106浏览量
    原文链接

  • 《LANCET，6月4日，Active case finding with case management: the key to tackling the COVID-19 pandemic》
    • 来源专题：COVID-19科研动态监测
    • 编译者：xuwenwhlib
    • 发布时间：2020-06-05
    • Active case finding with case management: the key to tackling the COVID-19 pandemic Prof Zhongjie Li, PhD * Qiulan Chen, PhD * Prof Luzhao Feng, PhD Lance Rodewald, MD Yinyin Xia, PhD Hailiang Yu, MMed et al. Show all authors Show footnotes Published:June 04, 2020DOI:https://doi.org/10.1016/S0140-6736(20)31278-2 Summary COVID-19 was declared a pandemic by WHO on March 11, 2020, the first non-influenza pandemic, affecting more than 200 countries and areas, with more than 5·9 million cases by May 31, 2020. Countries have developed strategies to deal with the COVID-19 pandemic that fit their epidemiological situations, capacities, and values. We describe China's strategies for prevention and control of COVID-19 (containment and suppression) and their application, from the perspective of the COVID-19 experience to date in China. Although China has contained severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and nearly stopped indigenous transmission, a strong suppression effort must continue to prevent re-establishment of community transmission from importation-related cases. We believe that case finding and management, with identification and quarantine of close contacts, are vitally important containment measures and are essential in China's pathway forward. We describe the next steps planned in China that follow the containment effort. We believe that sharing countries' experiences will help the global community manage the COVID-19 pandemic by identifying what works in the struggle against SARS-CoV-2.
    88浏览量
    原文链接