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《Nature，6月22日，Clinical epidemiological analyses of overweight/obesity and abnormal liver function contributing to prolonged hospitalization in patients infected with COVID-19》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-06-23

  • Clinical epidemiological analyses of overweight/obesity and abnormal liver function contributing to prolonged hospitalization in patients infected with COVID-19

    Xiang Hu, Xiaoqiong Pan, Wei Zhou, Xuejiang Gu, Feixia Shen, Bo Yang & Zhen Hu

    International Journal of Obesity (2020)

    Abstract

    Background/objectives

    During the 2019 coronavirus disease (COVID-19) outbreak, obesity may contribute to COVID-19 transmission and deterioration. In addition, many patients with COVID-19 infection have suffered liver damage which might contribute to a worse prognosis. We conducted a clinical epidemiological analysis to investigate the association of overweight/obesity and abnormal liver function (ALF) with hospitalized duration in patients infected with COVID-19.

    Subjects/methods

    Fifty-eight patients with diagnosed COVID-19 (22 women & 36 men; average age: 49.2 ± 13.1 yr) were included, and their clinical data were collected at The Second Affiliated and Yuying Children’s Hospital of Wenzhou Medical University, Zhejiang. Overweight/obesity was determined as body mass index (BMI) ≥24 kg/m2, ALF was determined as alanine aminotransferase >40 U/L, and prolonged hospitalization was lasting more than the median value of the hospitalized days (19 days) in this population.

  • 原文来源：https://www.nature.com/articles/s41366-020-0634-3
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  • 《6月22日_肥胖和肝功能损伤对COVID-19患者住院时长的影响》
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    • 编译者：xuwenwhlib
    • 发布时间：2020-06-23
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