《LANCET,3月11日,Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?》

  • 来源专题:COVID-19科研动态监测
  • 编译者: zhangmin
  • 发布时间:2020-03-12
  • Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

    Lei Fang

    George Karakiulakis

    Michael Roth

    Published:March 11, 2020DOI:https://doi.org/10.1016/S2213-2600(20)30116-8

    The most distinctive comorbidities of 32 non-survivors from a group of 52 intensive care unit patients with novel coronavirus disease 2019 (COVID-19) in the study by Xiaobo Yang and colleagues1 were cerebrovascular diseases (22%) and diabetes (22%). Another study2 included 1099 patients with confirmed COVID-19, of whom 173 had severe disease with comorbidities of hypertension (23·7%), diabetes mellitus (16·2%), coronary heart diseases (5·8%), and cerebrovascular disease (2·3%). In a third study,3 of 140 patients who were admitted to hospital with COVID-19, 30% had hypertension and 12% had diabetes.

  • 原文来源:https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30116-8/fulltext
相关报告
  • 《LANCET,3月3日,Risk of COVID-19 for patients with cancer》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-04
    • Risk of COVID-19 for patients with cancer Hanping Wang, Li Zhang Published:March 03, 2020DOI:https://doi.org/10.1016/S1470-2045(20)30149-2 The outbreak of coronavirus disease 2019 (COVID-19) is of international concern. We appreciated the Comment from Wenhua Liang and colleagues1 published in The Lancet Oncology on Feb 14, 2020, which, to the best of our knowledge, was the first to focus on COVID-19 infection in patients with cancer.
  • 《MedRxiv,3月24日,Hypertension and Diabetes Delay the Viral Clearance in COVID-19 Patients》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-25
    • Hypertension and Diabetes Delay the Viral Clearance in COVID-19 Patients Xiaoping Chen, Wenjia Hu, Jiaxin Ling, Pingzheng Mo, Yongxi Zhang, Qunqun Jiang, Zhiyong Ma, Qian Cao, Liping Deng, Shihui Song, Ruiying Zheng, Shicheng Gao, Hengning Ke, Xien Gui, Åke Lundkvist, Jinlin Li, Johanna F Lindahl, Yong Xiong doi: https://doi.org/10.1101/2020.03.22.20040774 Abstract Objectives: Comorbidities have significant indications for the disease outcome of COVID-19, however which underlying diseases that contribute the most to aggravate the conditions of COVID-19 patients is still largely unknown. SARS-CoV-2 viral clearance is a golden standard for defining the recovery of COVID-19 infections. To dissect the underlying diseases that could impact on viral clearance, we enrolled 106 COVID-19 patients who were hospitalized in the Zhongnan Hospital of Wuhan University, Wuhan, China between Jan 5 and Feb 25, 2020. Methodology: We comprehensively analyzed demographic, clinical and laboratory data, as well as patient treatment records. Survival analyses with Kaplan-Meier and Cox regression modelling were employed to identify factors influencing the viral clearance negatively. Results: We found that increasing age, male gender, and angiotensin-converting enzyme 2 (ACE2) associated factors (including hypertension, diabetes, and cardiovascular diseases) adversely affected the viral clearance. *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.