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《SSRN，3月18日，Non-Severe vs Severe Symptomatic COVID-19: 104 Cases from the Outbreak on the Cruise Ship 'Diamond Princess' in Japan》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-03-21

  • Non-Severe vs Severe Symptomatic COVID-19: 104 Cases from the Outbreak on the Cruise Ship 'Diamond Princess' in Japan

    19 Pages Posted: 18 Mar 2020

    Sakiko Tabata

    Self-Defense Forces Central Hospital

    Kazuo Imai

    Self-Defense Forces Central Hospital

    Abstract

    Background: The ongoing outbreak of 2019 novel coronavirus disease (COVID-19) is a global threat. Clarifying its clinical features such as risk factors for disease progression is a pressing issue. We analyzed the difference between non-severe and severe cases with COVID-19 as a result of the mass infection on a cruise ship “Diamond Princess” in Japan.

    Methods: In this retrospective, single-center study, total 104 cases of laboratory-confirmed COVID-19 were enrolled from the mass infection on the cruise ship from 11th to 25th Feb, 2020, at Self-Defense Forces Central Hospital in Japan. Clinical records, laboratory data, and radiological findings were collected and analyzed. Clinical outcomes were followed up until 26 th Feb, 2020.

  • 原文来源：https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3551331
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  • 《TLID，6月12日，Clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on the Diamond Princess cruise ship: a retrospective analysis》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-06-14
    • Clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on the Diamond Princess cruise ship: a retrospective analysis Author links open overlay panelSakikoTabataMDa†KazuoImaiMDab†ShuichiKawanoMDadMayuIkedaMDaTatsuyaKodamaMDaKazuyasuMiyoshiMDaHirofumiObinataMDacSatoshiMimuraMDaTsutomuKoderaMDaManabuKitagakiMDaMichiyaSatoMDaSatoshiSuzukiMDaToshimitsuItoMDaYasuhideUwabeMDaKakuTamuraMDa Show more https://doi.org/10.1016/S1473-3099(20)30482-5 Summary Background The ongoing COVID-19 pandemic is a global threat. Identification of markers for symptom onset and disease progression is a pressing issue. We described the clinical features of people infected on board the Diamond Princess cruise ship who were diagnosed with asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or mild or severe COVID-19, on admission to the Self-Defense Forces Central Hospital (Tokyo, Japan) and at the end of observation. Methods This retrospective, single-centre study included participants with laboratory-detected SARS-CoV-2 infection who were admitted to the Self-Defense Forces Central Hospital from Feb 11 to Feb 25, 2020. Clinical records, laboratory data, and radiological findings were analysed. Clinical outcomes were followed up until discharge or Feb 26, 2020, whichever came first. We defined asymptomatic infection as SARS-CoV-2 infection with no history of clinical signs and symptoms, severe COVID-19 as clinical symptoms of pneumonia (dyspnoea, tachypnoea, peripheral capillary oxygen saturation <93%, and need for oxygen therapy), and mild COVID-19 as all other symptoms. Clinical features on admission were compared among patients with different disease severity, including asymptomatic infection, at the end of observation. We used univariable analysis to identify factors associated with symptomatic illness among asymptomatic people infected with SARS-CoV-2 and disease progression in patients with COVID-19.
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  • 《MedRxiv，3月8日，Estimating the infection and case fatality ratio for COVID-19 using age-adjusted data from the outbreak on the Diamond Princess cruise ship》
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    • 编译者：zhangmin
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