Liver injury in COVID-19: management and challenges
Chao Zhang, Lei Shi, Fu-Sheng Wang
Published:March 04, 2020DOI:https://doi.org/10.1016/S2468-1253(20)30057-1
In December, 2019, an outbreak of a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], previously 2019-nCoV) started in Wuhan, China, and has since become a global threat to human health. The number of confirmed cases of 2019 coronavirus disease (COVID-19) has reached 87?137 worldwide as of March 1, 2020, according to WHO COVID-19 situation report 41; most of these patients are in Wuhan, China. Many cases of COVID-19 are acute and resolve quickly, but the disease can also be fatal, with a mortality rate of around 3%. Onset of severe disease can result in death due to massive alveolar damage and progressive respiratory failure.