《bioRxiv,6月7日,Rapid inactivation of SARS-CoV-2 with Deep-UV LED irradiation》

  • 来源专题:COVID-19科研动态监测
  • 编译者: xuwenwhlib
  • 发布时间:2020-06-09
  • Rapid inactivation of SARS-CoV-2 with Deep-UV LED irradiation

    Hiroko Inagaki, akatsuki Saito, Hironobu Sugiyama, Tamaki Okabayashi, Shouichi Fujimoto

    doi: https://doi.org/10.1101/2020.06.06.138149

    Abstract

    The spread of novel coronavirus disease 2019 (COVID-19) infections worldwide has raised concerns about the prevention and control of SARS-CoV-2. Devices that rapidly inactivate viruses can reduce the chance of infection through aerosols and contact transmission. This in vitro study demonstrated that irradiation with a deep ultraviolet light-emitting diode (DUV-LED) of 280 ± 5 nm wavelength rapidly inactivates SARS-CoV-2 obtained from a COVID-19 patient. Development of devices equipped with DUV-LED is expected to prevent virus invasion through the air and after touching contaminated objects.

    Competing Interest Statement

    The authors have declared no competing interest.

  • 原文来源:https://www.biorxiv.org/content/10.1101/2020.06.06.138149v1
相关报告
  • 《Nature,12月30日,Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2021-02-03
    • Rapid and complete inactivation of SARS-CoV-2 by ultraviolet-C irradiation Nadia Storm, Lindsay G. A. McKay, Sierra N. Downs, Rebecca I. Johnson, Dagnachew Birru, Marc de Samber, Walter Willaert, Giovanni Cennini & Anthony Griffiths Scientific Reports volume 10, Article number: 22421 (2020) Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has devastated global public health systems and economies, with over 52 million people infected, millions of jobs and businesses lost, and more than 1 million deaths recorded to date. Contact with surfaces contaminated with droplets generated by infected persons through exhaling, talking, coughing and sneezing is a major driver of SARS-CoV-2 transmission, with the virus being able to survive on surfaces for extended periods of time. To interrupt these chains of transmission, there is an urgent need for devices that can be deployed to inactivate the virus on both recently and existing contaminated surfaces. Here, we describe the inactivation of SARS-CoV-2 in both wet and dry format using radiation generated by a commercially available Signify ultraviolet (UV)-C light source at 254 nm. We show that for contaminated surfaces, only seconds of exposure is required for complete inactivation, allowing for easy implementation in decontamination workflows.
  • 《BioRxiv,3月7日,Direct RNA sequencing and early evolution of SARS-CoV-2》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-08
    • Direct RNA sequencing and early evolution of SARS-CoV-2 George Taiaroa, Daniel Rawlinson, Leo Featherstone, Miranda Pitt, Leon Caly, Julian Druce, Damian Purcell, Leigh Harty, Thomas Tran, Jason Roberts, Mike Catton, Deborah Williamson, Lachlan Coin, Sebastian Duchene doi: https://doi.org/10.1101/2020.03.05.976167 Abstract The rapid sharing of sequence information as seen throughout the current SARS-CoV-2 epidemic, represents an inflection point for genomic epidemiology. Here we describe aspects of coronavirus evolutionary genetics revealed from these data, and provide the first direct RNA sequence of SARS-CoV-2, detailing coronaviral subgenome-length mRNA architecture. *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.