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《MedRxiv，2月23日，Clinical characteristics of 50404 patients with 2019-nCoV infection》

  • 来源专题：COVID-19科研动态监测
  • 编译者： xuwenwhlib
  • 发布时间：2020-02-24

  • Clinical characteristics of 50404 patients with 2019-nCoV infection

    Pengfei Sun, Shuyan Qie, Zongjan Liu, Jizhen Ren, Jianing Jianing Xi

    doi: https://doi.org/10.1101/2020.02.18.20024539

    Abstract

    Objective: To provide reliable evidence of evidence-based medicine for the treatment and prevention of the 2019 novel coronavirus(2019-nCoV) by analyzing all the published studies on the clinical characteristics of patients with 2019-nCoV. Methods: PubMed,Cochrane Library,Embase and other databases were searched. Some studies on the clinical characteristics of 2019-nCoV infection were collected for Meta-analysis .Results: 9 studies were included in Meta-analysis, including a total of 50404 patients with 2019-nCoV infection.According to Meta-analysis, among the clinical characteristics of patients with 2019-nCoV infection, the incidence of fever is 90.9% , the incidence of cough is 70.8%, and the incidence of muscle soreness or fatigue is 41%. The incidence of acute respiratory distress syndrome (ARDS) was 14.8%, the incidence of abnormal chest CT was 95.6%, the proportion of severe cases in all infected cases was 21.3%, and the mortality rate of patients with 2019-nCoV infection was 4.8%. Conclusion: Fever and cough are the most common symptoms in patients with 2019-nCoV infection, and most of them have abnormal chest CT examination.Some people have muscle soreness or fatigue, ARDS. Diarrhea, hemoptysis, headache, sore throat, shock and other symptoms only occur in a small number of patients.The mortality rate of patients with 2019-nCoV infection was lower than that of Severe Acute Respiratory Syndrome (SRAS) and Middle East Respiratory Syndrome (MERS).

    *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.

  • 原文来源：https://www.medrxiv.org/content/10.1101/2020.02.18.20024539v1
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