Clinical trial analysis of 2019‐nCoV therapy registered in China
Qi Zhang Yakun Wang Changsong Qi Lin Shen Jian Li
First published:28 February 2020 https://doi.org/10.1002/jmv.25733
Abstract
So far, there is a lack of effective drugs for the new coronavirus pneumonia. With more and more patients diagnosed, China has carried out more than one hundred clinical studies of new coronavirus infection, including antiviral drugs, antimalarial drugs, glucocorticoids, plasma therapy, virus vaccine and other western drugs, while Chinese medicine researches accounted for half of studies. Most of the trials were initiated by investigators and the study period would last for one to eleven months. The primary endpoints included symptom improvement and virus nucleic acid turning negative, but the optimal endpoint has not been determined. Although the final results of studies will take a long time to complete, the interim research data may provide some help for the current urgent demand for drug treatment. Compared with that of during SARS period in 2003, China have the stronger capability to carry out clinical trials of new drugs in emergency period.