《JAMA,5月6日,Estimated Demand for US Hospital Inpatient and Intensive Care Unit Beds for Patients With COVID-19 Based on Comparisons With Wuhan and Guangzhou, China》

  • 来源专题:COVID-19科研动态监测
  • 编译者: xuwenwhlib
  • 发布时间:2020-05-07
  • Estimated Demand for US Hospital Inpatient and Intensive Care Unit Beds for Patients With COVID-19 Based on Comparisons With Wuhan and Guangzhou, China

    Ruoran Li, MPhil1; Caitlin Rivers, PhD2; Qi Tan, MD, PhD3,4; et alMegan B. Murray, DPH, MD3; Eric Toner, MD2; Marc Lipsitch, DPhil1

    Author Affiliations Article Information

    JAMA Netw Open. 2020;3(5):e208297. doi:10.1001/jamanetworkopen.2020.8297

    Abstract

    Importance Sustained spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has happened in major US cities. Capacity needs in cities in China could inform the planning of local health care resources.

    Objectives To describe and compare the intensive care unit (ICU) and inpatient bed needs for patients with coronavirus disease 2019 (COVID-19) in 2 cities in China to estimate the peak ICU bed needs in US cities if an outbreak equivalent to that in Wuhan occurs.

    Design, Setting, and Participants This comparative effectiveness study analyzed the confirmed cases of COVID-19 in Wuhan and Guangzhou, China, from January 10 to February 29, 2020.

    Exposures Timing of disease control measures relative to timing of SARS-CoV-2 community spread.

    Main Outcomes and Measures Number of critical and severe patient–days and peak number of patients with critical and severe illness during the study period.

    Results In Wuhan, strict disease control measures were implemented 6 weeks after sustained local transmission of SARS-CoV-2. Between January 10 and February 29, 2020, patients with COVID-19 accounted for a median (interquartile range) of 429 (25-1143) patients in the ICU and 1521 (111-7202) inpatients with serious illness each day. During the epidemic peak, 19?425 patients (24.5 per 10?000 adults) were hospitalized, 9689 (12.2 per 10?000 adults) were considered in serious condition, and 2087 (2.6 per 10?000 adults) needed critical care per day. In Guangzhou, strict disease control measures were implemented within 1 week of case importation. Between January 24 and February 29, COVID-19 accounted for a median (interquartile range) of 9 (7-12) patients in the ICU and 17 (15-26) inpatients with serious illness each day. During the epidemic peak, 15 patients were in critical condition and 38 were classified as having serious illness. The projected number of prevalent critically ill patients at the peak of a Wuhan-like outbreak in US cities was estimated to range from 2.2 to 4.4 per 10?000 adults, depending on differences in age distribution and comorbidity (ie, hypertension) prevalence.

  • 原文来源:https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2765575
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  • 《MedRxiv,3月13日,The demand for inpatient and ICU beds for COVID-19 in the US: lessons from Chinese cities》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-14
    • The demand for inpatient and ICU beds for COVID-19 in the US: lessons from Chinese cities Ruoran Li, Caitlin Rivers, Qi Tan, Megan B Murray, Eric Toner, Marc Lipsitch doi: https://doi.org/10.1101/2020.03.09.20033241 Abstract Background: Sustained spread of SARS-CoV-2 has happened in major US cities. Capacity needs in Chinese cities could inform the planning of local healthcare resources. Methods: We described the intensive care unit (ICU) and inpatient bed needs for confirmed COVID-19 patients in two Chinese cities (Wuhan and Guangzhou) from January 10 to February 29, 2020, and compared the timing of disease control measures in relation to the timing of SARS-CoV-2 community spread. We estimated the peak ICU bed needs in US cities if a Wuhan-like outbreak occurs. *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.
  • 《JAMA,5月1日,Assessment of QT Intervals in a Case Series of Patients With COVID-19 Infection Treated With Hydroxychloroquine Alone or in Combination With Azithromycin in an Intensive Care Unit》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-05-02
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