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《MedRixv，3月5日，（第2版更新）Genomic variations of SARS-CoV-2 suggest multiple outbreak sources of transmission》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-03-06

  • Genomic variations of SARS-CoV-2 suggest multiple outbreak sources of transmission

    Liangsheng Zhang, Jian-Rong Yang, Zhenguo Zhang, Zhenguo Lin

    doi: https://doi.org/10.1101/2020.02.25.20027953

    Abstract

    We examined 169 genomes of SARS-CoV-2 and found that they can be classified into two major genotypes, Type I and Type II. Type I can be further divided into Type IA and IB. Our phylogenetic analysis showed that the Type IA resembles the ancestral SARS-CoV-2 most. Type II was likely evolved from Type I and predominant in the infections. Our results suggest that Type II SARS-CoV-2 was the source of the outbreak in the Wuhan Huanan market and it was likely originated from a super-spreader.

    *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.

  • 原文来源：https://www.medrxiv.org/content/10.1101/2020.02.25.20027953v2
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