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《Inter Immunoph，6月26日，Analysis of Adjunctive Serological Detection to Nucleic Acid Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Diagnosis》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-06-27

  • Analysis of Adjunctive Serological Detection to Nucleic Acid Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Diagnosis

    Author links open overlay panelRuiLiua1XinghuiLiub1LiYuanc1HuanHanaMuhammadAdnan ShereendJieshengZhenaZhiliNiuaDongLiaFangLiudeKailangWucZhenLuofChengliangZhua

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    https://doi.org/10.1016/j.intimp.2020.106746

    Abstract

    Background

    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused coronavirus disease 2019 (COVID-19) epidemic in China, December 2019. The clinical features and treatment of COVID-19 patients remain largely elusive. However, accurate detection is required for SARS-CoV-2 infection diagnosis. We aimed to evaluate the antibodies-based test and nucleic acid-based test for SARS-CoV-2-infected patients.

    Methods

    We retrospectively studied 133 patients diagnosed with SARS-CoV-2 and admitted to Renmin Hospital of Wuhan University, China, from January 23 to March 1, 2020. Demographic data, clinical records, laboratory tests, and outcomes were collected. Data were accessed by SARS-CoV-2 IgM-IgG antibody test and real-time reverse transcriptase PCR (RT-PCR) detection for SARS-CoV-2 nucleic acid in COVID-19 patients.

  • 原文来源：https://www.sciencedirect.com/science/article/pii/S1567576920313692
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