登录
 机构网站
  1. 首页
  2. 情报产品
  3. 快讯详情

《Inter Immunoph，6月26日，Analysis of Adjunctive Serological Detection to Nucleic Acid Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Diagnosis》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-06-27

  • Analysis of Adjunctive Serological Detection to Nucleic Acid Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Diagnosis

    Author links open overlay panelRuiLiua1XinghuiLiub1LiYuanc1HuanHanaMuhammadAdnan ShereendJieshengZhenaZhiliNiuaDongLiaFangLiudeKailangWucZhenLuofChengliangZhua

    Show more

    https://doi.org/10.1016/j.intimp.2020.106746

    Abstract

    Background

    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused coronavirus disease 2019 (COVID-19) epidemic in China, December 2019. The clinical features and treatment of COVID-19 patients remain largely elusive. However, accurate detection is required for SARS-CoV-2 infection diagnosis. We aimed to evaluate the antibodies-based test and nucleic acid-based test for SARS-CoV-2-infected patients.

    Methods

    We retrospectively studied 133 patients diagnosed with SARS-CoV-2 and admitted to Renmin Hospital of Wuhan University, China, from January 23 to March 1, 2020. Demographic data, clinical records, laboratory tests, and outcomes were collected. Data were accessed by SARS-CoV-2 IgM-IgG antibody test and real-time reverse transcriptase PCR (RT-PCR) detection for SARS-CoV-2 nucleic acid in COVID-19 patients.

  • 原文来源：https://www.sciencedirect.com/science/article/pii/S1567576920313692
15浏览量
原文链接
相关报告

  • 《MedRxiv，3月10日，Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-03-11
    • Diagnosis of Acute Respiratory Syndrome Coronavirus 2 Infection by Detection of Nucleocapsid Protein Bo Diao, Kun Wen, JIAN CHEN, Yueping Liu, Zilin Yuan, Chao Han, Jiahui Chen, Yuxian Pan, Li Chen, Yunjie Dan, Jing Wang, Yongwen Chen, Guohong Deng, Hongwei Zhou, Yuzhang Wu doi: https://doi.org/10.1101/2020.03.07.20032524 Abstract BACKGROUND Nucleic acid test and antibody assay have been employed in the diagnosis for SARS-CoV-2 infection, but the use of viral antigen for diagnosis has not been successfully developed. Theoretically, viral antigen is the specific marker of the virus and precedes antibody appearance within the infected population. There is a clear need of detection of viral antigen for rapid and early diagnosis. METHODS We included a cohort of 239 participants with suspected SARS-CoV-2 infection from 7 centers for the study. *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.
    40浏览量
    原文链接

  • 《MedRxiv，3月6日，Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection》
    • 来源专题：COVID-19科研动态监测
    • 编译者：zhangmin
    • 发布时间：2020-03-07
    • Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Bo Diao, Zeqing Feng, Chenhui Wang, Huiming Wang, Liang Liu, Changsong Wang, Rongshuai Wang, Ying Liu, Yueping Liu, Gang Wang, Zilin Yuan, Yuzhang Wu, Yongwen Chen doi: https://doi.org/10.1101/2020.03.04.20031120 Abstract BACKGROUND The coronavirus disease 2019 (COVID-19) is a newly emerged infection from the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Apart from the respiratory system, it is unclear whether SARS-CoV-2 can also directly infect other tissues such as the kidney or induce acute renal failure. METHODS We conducted a retrospective analysis of estimated glomerular filtration rate (eGFR), plasma creatinine, and urea concentrations along with other clinical parameters from 85 patients with laboratory-confirmed COVID-19 admitted to a hospital in Wuhan from January 17, 2020 to March 3, 2020. *注，本文为预印本论文手稿，是未经同行评审的初步报告，其观点仅供科研同行交流，并不是结论性内容，请使用者谨慎使用.
    47浏览量
    原文链接