This toolkit is a comprehensive set of practical tools and resources designed to support country-level risk communication and community engagement (RCCE) practitioners, decision-makers, and partners to plan and implement readiness and response activities for mpox (previously known as monkeypox). The toolkit contains: information about mpox; RCCE considerations for how to approach key issues during mpox outbreaks; tools for understanding the context in which mpox outbreaks occur; methods for collecting data to inform strategy development and bring evidence into planning and implementation of activities; case studies; and links to existing RCCE tools and training. It is one of a suite of toolkits on RCCE readiness and response to a range of disease and response areas.