《LANCET,4月8日,Recommendations from national regulatory agencies for ongoing cancer trials during the COVID-19 pandemic》

  • 来源专题:COVID-19科研动态监测
  • 编译者: zhangmin
  • 发布时间:2020-04-09
  • Recommendations from national regulatory agencies for ongoing cancer trials during the COVID-19 pandemic

    Bruno H R de Paula

    Indiara Araújo

    Lívia Bandeira

    Nathália M P B Barreto

    Gary J Doherty

    Published:April 08, 2020DOI:https://doi.org/10.1016/S1470-2045(20)30226-6

    Clinical research has transformed cancer care and is often integrated seamlessly into routine oncology clinics, offering eligible patients additional treatment options or lines of therapy. Typically, and particularly for diseases with poor prognoses or when trials entail biomarker-directed personalised treatment, clinical trial enrolment can be preferred (by both doctors and patients) over standard care.

  • 原文来源:https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(20)30226-6/fulltext
相关报告
  • 《LANCET,4月9日,Delayed access or provision of care in Italy resulting from fear of COVID-19》

    • 来源专题:COVID-19科研动态监测
    • 编译者:xuwenwhlib
    • 发布时间:2020-04-10
    • Delayed access or provision of care in Italy resulting from fear of COVID-19 Marzia Lazzerini Egidio Barbi Andrea Apicella Federico Marchetti Fabio Cardinale Gianluca Trobia Published:April 09, 2020DOI:https://doi.org/10.1016/S2352-4642(20)30108-5 During Italy's national lockdown for coronavirus disease 2019 (COVID-19), official hospital statistics in the period March 1–27, 2020, show substantial decreases—ranging from 73% to 88%—in paediatric emergency department visits compared with the same time period in 2019 and 2018 (figure). Similarly, family paediatricians widely report a considerable reduction in clinic visits, although this is difficult to measure precisely.
  • 《LANCET,4月6日,Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations》

    • 来源专题:COVID-19科研动态监测
    • 编译者:xuwenwhlib
    • 发布时间:2020-04-07
    • Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations Jason Phua, MRCP,Li Weng, MD,Lowell Ling, MRCP,Moritoki Egi, MD,Prof Chae-Man Lim, MD,Prof Jigeeshu Vasishtha Divatia, MD Published:April 06, 2020DOI:https://doi.org/10.1016/S2213-2600(20)30161-2 As coronavirus disease 2019 (COVID-19) spreads across the world, the intensive care unit (ICU) community must prepare for the challenges associated with this pandemic. Streamlining of workflows for rapid diagnosis and isolation, clinical management, and infection prevention will matter not only to patients with COVID-19, but also to health-care workers and other patients who are at risk from nosocomial transmission. Management of acute respiratory failure and haemodynamics is key. ICU practitioners, hospital administrators, governments, and policy makers must prepare for a substantial increase in critical care bed capacity, with a focus not just on infrastructure and supplies, but also on staff management. Critical care triage to allow the rationing of scarce ICU resources might be needed. Researchers must address unanswered questions, including the role of repurposed and experimental therapies. Collaboration at the local, regional, national, and international level offers the best chance of survival for the critically ill.