Transmission of corona virus disease 2019 during the incubation period may lead to a quarantine loophole
Wei Xia, Jiaqiang Liao, Chunhui Li, Yuanyuan Li, Xi Qian, Xiaojie Sun, Hongbo Xu, Gaga Mahai, Xin Zhao, Lisha Shi, Juan Liu, Ling Yu, Meng Wang, Qianqian Wang, Asmagvl Namat, Ying Li, Jingyu Qu, Qi Liu, Xiaofang Lin, Shuting Cao, Shu Huan, Jiying Xiao, Fengyu Ruan, Hanjin Wang, Qing Xu, Xingjuan Ding, Xingjie Fang, Feng Qiu, Jiaolong Ma, Yu Zhang, Aizhen Wang, Yuling Xing, Shunqing Xu
doi: https://doi.org/10.1101/2020.03.06.20031955
Abstract
Background: The ongoing outbreak of novel corona virus disease 2019 (COVID-19) in Wuhan, China, is arousing international concern. This study evaluated whether and when the infected but asymptomatic cases during the incubation period could infect others. Methods: We collected data on demographic characteristics, exposure history, and symptom onset day of the confirmed cases, which had been announced by the Chinese local authorities. We evaluated the potential of transmission during the incubation period in 50 infection clusters, including 124 cases. All the secondary cases had a history of contact with their first-generation cases prior to symptom onset.
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