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《JAMA，6月26日，Clinical Characteristics and Outcomes in Patients With Coronavirus Disease 2019 and Multiple Sclerosis》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-06-28

  • Clinical Characteristics and Outcomes in Patients With Coronavirus Disease 2019 and Multiple Sclerosis
    Céline Louapre, MD1; Nicolas Collongues, MD2; Bruno Stankoff, MD1,3; et al Claire Giannesini, MD3; Caroline Papeix, MD1; Caroline Bensa, MD4; Romain Deschamps, MD4; Alain Créange, MD5; Abir Wahab, MD5; Jean Pelletier, MD6; Olivier Heinzlef, MD7; Pierre Labauge, MD8; Laurent Guilloton, MD9; Guido Ahle, MD10; Mathilde Goudot, MD11; Kevin Bigaut, MD2; David-Axel Laplaud, MD12; Sandra Vukusic, MD13; Catherine Lubetzki, MD1; Jérôme De Sèze, MD2; for the Covisep investigators
    Author Affiliations Article Information
    JAMA Neurol. Published online June 26, 2020. doi:10.1001/jamaneurol.2020.2581

    Abstract
    Importance  Risk factors associated with the severity of coronavirus disease 2019 (COVID-19) in patients with multiple sclerosis (MS) are unknown. Disease-modifying therapies (DMTs) may modify the risk of developing a severe COVID-19 infection, beside identified risk factors such as age and comorbidities.

    Objective  To describe the clinical characteristics and outcomes in patients with MS and COVID-19 and identify factors associated with COVID-19 severity.

    Design, Setting, and Participants  The Covisep registry is a multicenter, retrospective, observational cohort study conducted in MS expert centers and general hospitals and with neurologists collaborating with MS expert centers and members of the Société Francophone de la Sclérose en Plaques. The study included patients with MS presenting with a confirmed or highly suspected diagnosis of COVID-19 between March 1, 2020, and May 21, 2020.

  • 原文来源：https://jamanetwork.com/journals/jamaneurology/fullarticle/2767776?resultClick=1
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