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《Nature，4月3日，Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-04-04

  • Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic

    Andrew M. South, Laurie Tomlinson, Daniel Edmonston, Swapnil Hiremath & Matthew A. Sparks

    Nature Reviews Nephrology (2020)

    The current COVID-19 pandemic is associated with unprecedented morbidity and mortality. Early reports suggested an association between disease severity and hypertension but did not account for sources of confounding. However, the responsible virus — SARS-CoV-2 — gains entry to host cells via angiotensin-converting enzyme 2 (ACE2), highlighting the need to understand the relationship between the virus and the renin–angiotensin system (RAS) and how this might be affected by RAS inhibitors.

  • 原文来源：https://www.nature.com/articles/s41581-020-0279-4
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