A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification System
Author links open overlay panelYiminZhangaLiangYuaLingLingTangbMengfeiZhubYanqiJinaZhouhanWangaLanjuanLia
Show more
https://doi.org/10.1016/j.eng.2020.03.006
Introduction
The Corona Virus Disease 2019 (COVID-19) pan-epidemic, resulting from infection with the novel coronavirus 2019-nCoV (also known as severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)), is currently the source of public health concern worldwide; however, treatment of this infection has been clinically challenging in many patients [1], [2]. Importantly, 2019-nCoV is the third fatal coronavirus that has emerged in the past two decades, following SARS and the Middle East respiratory syndrome (MERS) [2], [3]. The numbers of confirmed cases of COVID-19 infection and related deaths are still rising. As of 9 March 2020, there have been 80 754 confirmed cases and 3136 deaths in mainland China alone [4], corresponding to a total crude mortality of 3.88%.