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《Current Biology，3月19日，Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-03-20

  • Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak

    TaoZhang12QunfuWu12ZhigangZhang13

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    https://doi.org/10.1016/j.cub.2020.03.022

    Summary

    An outbreak of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) began in the city of Wuhan in China and has widely spread worldwide. Currently, it is vital to explore potential intermediate hosts of SARS-CoV-2 to control COVID-19 spread. Therefore, we reinvestigated published data from pangolin lung samples from which SARS-CoV-like CoVs were detected by Liu et al. [1]. We found genomic and evolutionary evidence of the occurrence of a SARS-CoV-2-like CoV (named Pangolin-CoV) in dead Malayan pangolins. Pangolin-CoV is 91.02% and 90.55% identical to SARS-CoV-2 and BatCoV RaTG13, respectively, at the whole-genome level. Aside from RaTG13, Pangolin-CoV is the most closely related CoV to SARS-CoV-2.

  • 原文来源：https://www.sciencedirect.com/science/article/pii/S0960982220303602
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