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《LANCET，3月23日，Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-03-24

  • Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

    Kelvin Kai-Wang To, MD †

    Owen Tak-Yin Tsang, FRCP †

    Wai-Shing Leung, FRCP

    Anthony Raymond Tam, MRCP

    Tak-Chiu Wu, FRCP

    David Christopher Lung, FRCPath

    et al.

    Published:March 23, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30196-1

    Summary

    Background

    Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial outbreaks. Comprehensive data for serial respiratory viral load and serum antibody responses from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not yet available. Nasopharyngeal and throat swabs are usually obtained for serial viral load monitoring of respiratory infections but gathering these specimens can cause discomfort for patients and put health-care workers at risk. We aimed to ascertain the serial respiratory viral load of SARS-CoV-2 in posterior oropharyngeal (deep throat) saliva samples from patients with COVID-19, and serum antibody responses.

  • 原文来源：https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30196-1/fulltext
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