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《INFECTION，3月5日，Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2》

  • 来源专题：COVID-19科研动态监测
  • 编译者： zhangmin
  • 发布时间：2020-03-08

  • Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2

    FengWen, HaiYu, JinyueGuo, YongLi, KaijianLuo, ShujianHuang

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    https://doi.org/10.1016/j.jinf.2020.02.027

    Dear editor

    A recent study in this journal studied the genomes of the novel SARS-like coronavirus (SARS-CoV-2) in China and suggested that the SARS-CoV-2 had undergone genetic recombination with SARS-related CoV1. By February 14, 2020, a total of 66,576 confirmed cases of COVID-19, people infected with SARS-CoV-2, were reported in China, leading to 1,524 deaths, per the Chinese CDC (http://2019ncov.chinacdc.cn/2019-nCoV/). Several full genomic sequences of this virus have been released for the study of its evolutionary origin and molecular characteristics2, 3, 4. Here, we analyzed the potential mutations that may have evolved after the virus became epidemic among humans and also the mutations resulting in the human adaptation.

  • 原文来源：https://www.sciencedirect.com/science/article/pii/S0163445320301080
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