《BioRxiv,3月10日,Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak》

  • 来源专题:COVID-19科研动态监测
  • 编译者: zhangmin
  • 发布时间:2020-03-11
  • Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak

    Yuan Liu, Zhi Ning, Yu Chen, Ming Guo, Yingle Liu, Nirmal Kumar Gali, Li Sun, Yusen Duan, Jing Cai, Dane Westerdahl, Xinjin Liu, Kin-fai Ho, Haidong Kan, Qingyan Fu, Ke Lan

    doi: https://doi.org/10.1101/2020.03.08.982637

    Abstract

    Background: The ongoing outbreak of COVID-19 has spread rapidly and sparked global concern. While the transmission of SARS-CoV-2 through human respiratory droplets and contact with infected persons is clear, the aerosol transmission of SARS-CoV-2 has been little studied. Methods: Thirty-five aerosol samples of three different types (total suspended particle, size segregated and deposition aerosol) were collected in Patient Areas (PAA) and Medical Staff Areas (MSA) of Renmin Hospital of Wuhan University (Renmin) and Wuchang Fangcang Field Hospital (Fangcang), and Public Areas (PUA) in Wuhan, China during COVID-19 outbreak.

    *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用.

  • 原文来源:https://www.biorxiv.org/content/10.1101/2020.03.08.982637v1
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  • 《Nature,4月27日,Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-04-28
    • Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals Yuan Liu, Zhi Ning, Yu Chen, Ming Guo, Yingle Liu, Nirmal Kumar Gali, Li Sun, Yusen Duan, Jing Cai, Dane Westerdahl, Xinjin Liu, Ke Xu, Kin-fai Ho, Haidong Kan, Qingyan Fu & Ke Lan Nature (2020) Abstract The ongoing COVID-19 outbreak has spread rapidly on a global scale. While the transmission of SARS-CoV-2 via human respiratory droplets and direct contact is clear, the potential for aerosol transmission is poorly understood1–3. This study investigated the aerodynamic nature of SARS-CoV-2 by measuring viral RNA in aerosols in different areas of two Wuhan hospitals during the COVID-19 outbreak in February and March 2020. The concentration of SARS-CoV-2 RNA in aerosols detected in isolation wards and ventilated patient rooms was very low, but it was elevated in the patients’ toilet areas. Levels of airborne SARS-CoV-2 RNA in the majority of public areas was undetectable except in two areas prone to crowding, possibly due to infected carriers in the crowd.
  • 《3月10日_COVID-19暴发期间武汉医院SARS-CoV-2气溶胶的空气动力学特征和RNA浓度》

    • 来源专题:COVID-19科研动态监测
    • 编译者:zhangmin
    • 发布时间:2020-03-12
    • 1.时间:2020年3月10日 2.机构或团队:武汉大学;香港科技大学;上海环境监测中心;复旦大学; 香港中文大学 3. 事件概要: bioRxiv预印平台于3月10日发表了武汉大学等发表的论文“Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak”。文章陈,虽然SARS-CoV-2通过人的飞沫和与感染者接触的传播是清楚的,但对SARS-CoV-2的气溶胶传播研究甚少。 研究人员在COVID-19暴发期间的的武汉大学人民医院、武昌方舱医院患者区(PAA)和医务人员区(MSA)和武汉公共区域(PUA)收集了35种三种不同类型的气溶胶样品(总悬浮颗粒、尺寸分离的以及沉积气溶胶)。采用微滴式数字聚合酶链反应(ddPCR)方法定量检测病毒SARS-CoV-2 RNA基因组,并测定气溶胶RNA浓度。 该研究结果显示,ICU,CCU和人民医院内的普通病房,方舱内的患者大厅空气中的检测不到SARS-CoV-2或浓度较低,但ICU内的沉积物样品和方舱医院患者厕所中的空气样品检测为阳性。疫情暴发期间,方舱医务人员区(MSA)中的空气传播SARS-CoV-2具有双峰分布且其浓度高于人民医院的医务人员区,但在患者人数减少和实施了严格的消毒后变为阴性。武汉公共区域在空气中检测不到SARS-CoV-2,但随着人群流量的增加而明显增加。 文章总结成,室内通风、开放空间、厕所的正确使用和消毒可以有效地限制SARS-CoV-2气溶胶的传播。聚集无症状携带者人群是空气传播SARS-CoV-2的潜在来源。病毒气溶胶沉积在防护服或地板表面及其随后的再悬浮是一种潜在的传播途径,有效的消毒对最大限度地减少SARS-CoV-2的气溶胶传播至关重要。 *注,本文为预印本论文手稿,是未经同行评审的初步报告,其观点仅供科研同行交流,并不是结论性内容,请使用者谨慎使用。 4.附件 原文链接:https://www.biorxiv.org/content/10.1101/2020.03.08.982637v1