The results of the pharmacovigilance system operation in Vinnytsia region during 2016 are presented based on the data of the electronic online system "Pharmacovigilance-2016", which was first introduced by us on the basis of the table editor Microsoft Excel of the file-hosting system Google Drive. The formula for calculating the efficiency of the pharmacovigilance implementation as an integral assessment of the safety oversight of medical devices in their use in Vinnytsia region during 2016 is proposed, taking into account the capacity of health facilities at the local level.
The data of the literature and the results of original experimental observations concerning the age aspects of stress reactions that accompany a person from birth to adulthood are given. Stress in children is emotional and is characterized by an increase in the thymus, as well as an increase in the level of corticosteroids in the blood, as a reflection of the innate immune-lymphoid defense of the child, which occurs in the process of the childbirth stress of mother. Other indicators of neurohormonal protection (adrenal glands, spleen, eosinopenia, hyperglycemia) are typical but less pronounced than in adults due to functional immaturity of systems and organs. The shift in the balance of the prooxidant-antioxidant system is not marked. In addition, "child" stress is manifested by deficiency of magnesium (Mg2+), a violation of the acid balance and immune deficiency. The above data serve as the basis for the proof of the need of involving in everyday complex therapy of any disease, depending on the indications, along with formulary preparations in children's doses of herbal sedatives (Valeriana officinalis, Cardamine pratensis), psycho-responsive tranquilizers and even neuroleptics, magnesium preparations, Echinacea in combination with Zinc and vitamin C. Also antioxidants, immunostimulants and stressors (piracetam, aminolon, taurine), plant adaptogenes (Panax, Eleutherococcus), which prevent a stress reaction, without violating the level of innate protection of the growing organism and the child's mental abilities at the level of its physical development, are recommended.
The concept of trust and the main factors affecting it are analyzed. The essence of trust-based marketing and its tasks, the main strategies of building trust to an organization from the clients’ side are considered. The CRM system has been explored as a tool for managing customer relationships, and contemporary marketing technologies such as crowdsourcing and collaboration that develop trust are considered.
The article is devoted to the analysis of the trends of Internet marketing development. The differences between Internet marketing and traditional marketing in the conditions of modern economy and active spreading of the Internet are determined. The problems of changing the trading infrastructure, the emergence of new channels for the distribution of goods and services, the changing nature of marketing communications, the benefits of interactive marketing are displayed.
The purpose of the article is to improve the model of the enterprise (institution, organization) management process on the basis of general management functions. The graphic model of the process of management according to the process-structured management is presented. It has been established that in today's business environment, the model of the management process should include such general management functions as: 1) controlling the achievement of results; 2) planning based on the main goal; 3) coordination and corrective actions (in the system of organization of work and production); 4) action as a form of act (conscious, volitional, directed); 5) accounting system (accounting, statistical, operational-technical and managerial); 6) diagnosis (economic, legal) with such subfunctions as: identification of the state and capabilities; analysis (economic, legal, systemic) with argumentation; assessment of the state, trends and prospects of development. The prospect of further research in this direction is: 1) the formation of a system of interrelation of functions and management methods, taking into account the presented research results; 2) development of the model of effective and efficient communication business process of the enterprise.
The purpose of the article is to substantiate the theoretical positions and develop practical recommendations for improving the diagnostic toolkit of the enterprise's production program. The order (general scheme) of the production program of the enterprise is presented. It is proved that the production program of the enterprise determines the composition (from the nomenclature, the range and quality) and the volume of production in natural and value terms. It is established that in order to calculate the enterprise's production program in cost recovery, it is necessary to calculate the indicators of the volume of gross output, the volume of marketable products and the volume of sold products. It is revealed that the importance of the system of diagnostics of the production program of the enterprise is held by the calculation of the planned magnitude of the production capacity of the enterprise. The prospect of further research in this direction is to improve the polycriterial diagnostics of the prospects for the functioning of enterprises, taking into account the presented research results.
The article explores the problem of the systematic organization of the conceptual sphere of space as a fragment of the general conceptual system of the Greeks; describes the functional-semantic features of lexemes, that act as linguistic representatives of the concept sphere of space and are characterized by ethnospecific features of the ancient Greek language model of the world; the dependence of the formation of the body of lexemes of spatial semantics on the specificity of the perception of the environment by the native speakers of the ancient Greek language is established. The principles of the analysis of the spatial vocabulary of the ancient Greek language presented in this article are a sample of systemic-structural, functional-semantic and conceptual analysis of linguistic units and they can become the basis for theoretical, practical and historical grammars of the Greek language, comparative typology of Indo-European languages, and possible practical developments in the field of linguistic conceptology.
The article is devoted to the theoretical substantiation of the essence of public marketing and its impact on the interaction of state organizations and society. On the basis of analysis, generalization and systematization of scientific sources, the main theoretical aspects of the interaction of public organizations with private enterprises and society are highlighted.
The purpose of the article is to develop a model of the system of managerial diagnostics of the enterprise on the basis of the improvement of diagnostic purposes. The developed model of the system of managerial diagnostics of the enterprise is a set of subjects (owners, managers, investors, specialists, etc.), objects (management system), resources, technology, methods (a set of methods and means), business indicators and criteria (parameters) that, when interacting, provide the achievement (efficient and effective) of the diagnostic objectives of the system of the objectives of managerial diagnostics of the enterprise, taking into account the compliance of its competitive strategy of the state of the environment function of direct action (competitors, customers, suppliers, mediators, and other contact audiences) in the context of improving the efficiency and developing the management. It is determined that the system of goals of the model of the system of managerial diagnostics of the enterprise (taking into account the ensuring of the compliance of the system of management with strategic goals and tactical tasks) form the following key diagnostic objectives that require improvement on the basis of business indicators (parameters), namely: 1) diagnostics of the effectiveness of controlling the internal business processes of the enterprise; 2) diagnostics of the effectiveness of the typical organizational structure of enterprise management; 3) diagnostics of the efficiency of standardization of the work of linear and functional managers and specialists at the enterprise; 4) diagnostics of the enterprise in the areas of vocational education, labor activity and motivation, innovation work and social development; 5) diagnostics of the level of conflict in the team at the enterprise; 6) diagnostics of efficiency of use of information technologies in the management of the enterprise. The prospect of further research in this area is to improve the complex system of diagnostics of certain elements, spheres and types of activity of enterprises, taking into account the presented research results.
The study is devoted to enlightening the difficulties of translation of the computer discourse vocabulary into the Ukrainian language. The work describes the main problems encountered by translators, users of the PC or the Internet, and identifies the appropriate ways to solve the problem, depending on the area of the taxonomy using.