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The Ecstasy and Agony of Assay Interference Compounds 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:60  Issue:6  Page:2165-2168  

Aldrich Courtney;   Bertozzi Carolyn;   Georg Gunda I;   Kiessling Laura;   Lindsley Craig;   ...

来源数据库: Scopus,

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2    
NaV1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine 期刊论文

Trends in Pharmacological Sciences     ISSN:0165-6147  Volume:39  Issue:3  Page:258-275  

Yang Yang;   Mis Malgorzata A;   Estacion Mark;   Dib-Hajj Sulayman D;   Waxman Stephen G;  

来源数据库: Scopus,

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3    
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimizat... 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:60  Issue:16  Page:7029-7042  

Swain Nigel. A;   Batchelor Dave;   Beaudoin Serge;   Bechle Bruce M;   Bradley Paul A;   ...

来源数据库: Scopus,

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4    
Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Rob... 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:60  Issue:14  Page:5990-6017  

Graceffa Russell F;   Boezio Alessandro A;   Able Jessica;   Altmann Steven;   Berry Loren M;   ...

来源数据库: Scopus,

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5    
Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy? 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:61  Issue:12  Page:5073-5092  

Philip Stephen;   Kumarasiri Malika;   Teo Theodosia;   Yu Mingfeng;   Wang Shudong;  

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6    
Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics while Mitigating Metabolic Liabilities 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:60  Issue:14  Page:5969-5989  

Weiss Matthew M;   Dineen Thomas A;   Marx Isaac E;   Altmann Steven;   Boezio Alessandro;   ...

来源数据库: Scopus,

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7    
Discovery of [cis -3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H -inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic ... 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:61  Issue:7  Page:2973-2988  

Kono Mitsunori;   Ochida Atsuko;   Oda Tsuneo;   Imada Takashi;   Banno Yoshihiro;   ...

来源数据库: Scopus,

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8    
Escherichia coli carrying IncX4 plasmid-mediated mcr-1 and blaCTX-M genes in infected migratory Magellanic penguins (Spheniscus magellanicus) 期刊论文

Journal of Antimicrobial Chemotherapy     ISSN:0305-7453  Volume:72  Issue:4  Page:1255-1256  

Sellera Fábio P;   Fernandes Miriam R;   Sartori Luciana;   Carvalho Marcelo P.N;   Esposito Fernanda;   ...

来源数据库: Scopus,

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9    
Design and Synthesis of γ- And δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:60  Issue:15  Page:6649-6663  

Davoren Jennifer E;   Garnsey Michelle;   Pettersen Betty;   Brodney Michael A;   Edgerton Jeremy R;   ...

来源数据库: Scopus,

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10    
Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H -pyrazolo[3,4- c] pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) ... 期刊论文

Journal of Medicinal Chemistry     ISSN:0022-2623  Volume:61  Issue:6  Page:2384-2409  

Yoshikawa Masato;   Saitoh Morihisa;   Katoh Taisuke;   Seki Tomohiro;   Bigi Simone V;   ...

来源数据库: Scopus,

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