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期刊名称: Human Brain Mapping
Volume:27    Issue:5        Page:392-401
ISSN:1065-9471

Analysis of Functional Image Analysis Contest (FIAC) data with BrainVoyager QX: From single-subject to cortically aligned group general linear model analysis and self-organizing group independent component analysis期刊论文

作者: Goebel R.W Esposito F Formisano E
DOI:10.1002/hbm.20249

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页码: 392-401
被引频次: 721
出版者: Wiley Subscription Services, Inc., A Wiley Company,WILEY-LISS
期刊名称: Human Brain Mapping
ISSN: 1065-9471
卷期: Volume:27    Issue:5
语言: English
摘要: The Functional Image Analysis Contest (FIAC) 2005 dataset was analyzed using BrainVoyager QX. First, we performed a standard analysis of the functional and anatomical data that includes preprocessing, spatial normalization into Talairach space, hypothesis‐driven statistics (one‐ and two‐factorial, single‐subject and group‐level random effects, General Linear Model [GLM]) of the block‐ and event‐related paradigms. Strong sentence and weak speaker group‐level effects were detected in temporal and frontal regions. Following this standard analysis, we performed single‐subject and group‐level (Talairach‐based) Independent Component Analysis (ICA) that highlights the presence of functionally connected clusters in temporal and frontal regions for sentence processing, besides revealing other networks related to auditory stimulation or to the default state of the brain. Finally, we applied a high‐resolution cortical alignment method to improve the spatial correspondence across brains and re‐run the random effects group GLM as well as the group‐level ICA in this space. Using spatially and temporally unsmoothed data, this cortex‐based analysis revealed comparable results but with a set of spatially more confined group clusters and more differential group region of interest time courses. Hum. Brain Mapp, 2006. © 2006 Wiley‐Liss, Inc.
相关主题: cortical alignment, independent component analysis, cortex‐based analysis, fMRI data analysis, functional magnetic resonance imaging, Functional magnetic resonance imaging, Cortex-based analysis, Cortical alignment, Independent component analysis, ALGORITHM, NEUROSCIENCES, NEUROIMAGING, cortex-based analysis, VOICE, TIME-SERIES, RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING, FMRI, BRAIN, Verbal Behavior - physiology, Magnetic Resonance Imaging - trends, Principal Component Analysis - standards, Humans, Magnetic Resonance Imaging - methods, Temporal Lobe - anatomy & histology, Nerve Net - physiology, Principal Component Analysis - methods, Frontal Lobe - physiology, Image Processing, Computer-Assisted - trends, Language, Software - trends, Cerebral Cortex - anatomy & histology, Software - standards, Reproducibility of Results, Linear Models, Brain Mapping - methods, Image Processing, Computer-Assisted - methods, Speech Perception - physiology, Algorithms, Language Tests, Nerve Net - anatomy & histology, Cerebral Cortex - physiology, Temporal Lobe - physiology, Frontal Lobe - anatomy & histology, Cohort Studies, Index Medicus,

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