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期刊名称: Research in Developmental Disabilities
Volume:55    Page:256-267
ISSN:0891-4222

Single blind randomised controlled trial of GAME (Goals ⿿ Activity ⿿ Motor Enrichment) in infants at high risk of cerebral palsy期刊论文

作者: Morgan Catherine Novak Iona Dale Russell C Guzzetta Andrea Badawi Nadia
DOI:10.1016/j.ridd.2016.04.005

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页码: 256-267
被引频次: 28
出版者: Elsevier Ltd,PERGAMON-ELSEVIER SCIENCE LTD,Elsevier B.V
期刊名称: Research in Developmental Disabilities
ISSN: 0891-4222
语言: English
摘要: Cerebral palsy (CP) is caused by a lesion in the developing infant brain. Recent neuroplasticity literature suggests that intensive, task-specific intervention ought to commence early, during the critical period of neural development. To determine whether ⿿GAME⿿ (Goals ⿿ Activity ⿿ Motor Enrichment), a motor learning, environmental enrichment intervention, is effective for improving motor skills in infants at high risk of CP. Single blind randomised controlled trial of GAME versus standard care. Primary outcome was motor skills on the Peabody Developmental Motor Scales-2 (PDMS-2). Secondary outcomes included Canadian Occupational Performance Measure (COPM), Bayley Scales of Infant and Toddler Development (BSID-III) and Gross Motor Function Measure-66 (GMFM-66). Outcome assessors were masked to group allocation and data analyzed with multiple regression. All n = 30 infants enrolled received the assigned intervention until 16 weeks post enrolment. At 12 months of age, n = 26 completed assessments. Significant between group differences were found in raw scores on the PDMS-2 in favour of GAME (B = 20.71, 95%CI 1.66⿿39.76, p = 0. 03) and at 12 months on the total motor quotient (B = 8.29, 95%CI 0.13⿿16.45,p = 0.05). Significant between group differences favored GAME participants at 12 months on the cognitive scale of the BSID-III and satisfaction scores on the COPM. GAME intervention resulted in advanced motor and cognitive outcomes when compared with standard care.
相关主题: Cerebral palsy, Early intervention, Motor learning, Environmental enrichment, PROGNOSIS, PROTOCOL, REHABILITATION, YOUNG-CHILDREN, EDUCATION, SPECIAL, AGE, Early Medical Intervention - methods, Single-Blind Method, Parents - education, Cerebral Palsy - epidemiology, Humans, Patient-Centered Care, Anxiety - psychology, Infant, Male, Risk, Cognition, Stress, Psychological - psychology, Learning, Parents - psychology, Neuronal Plasticity, Cerebral Palsy - rehabilitation, Depression - psychology, Environment, Female, Goals, Motor Skills, Neurosciences, Infants, Research institutes, Child development,

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