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作者 : Tian HY ;   Chen J ;   Chen XS ;  
关键词 : MOLECULAR-WEIGHT POLYETHYLENIMINE;MESOPOROUS SILICA NANOPARTICLES;CONJUGATED GOLD NANOPARTICLES;MULTIDRUG-RESISTANT CANCER;POLYLYSINE DNA COMPLEXES;SIRNA DELIVERY;IN-VIVO;PLASMID DNA;CO-DELIVERY;BLOCK-COPOLYMER;
出版者 : SMALL
ISN : 1613-6810
出版年 : 2013
卷 : 9
期 : 12
起始页码 : 2034
终止页码 : 2044
语种 : en
摘要 : Nanocarriers are a new type of nonviral gene carriers, many of which have demonstrated a broad range of pharmacological and biological properties, such as being biodegradable in the body, stimulus-responsive towards the surrounding environment, and an abiltiy to specifically targeting certain disease sites. By summarizing some main types of nanocarriers, this Concept considers the current status and possible future directions of the potential clinical applications of multifunctional nanocarriers, with primary attention on the combination of such properties as biodegradability, targetability, transfection ability, and stimuli sensitivity.

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